通讯作者文章

1.Zhou WJ#, Tang QS#, Wang SN#, Ding L,Chen M, Liu HM,Wu Y,Xiong XW,Shen ZY*,Chen WQ*. Local thiamet-G delivery by a thermosensitive hydrogel confers ischemic cardiac repair via myeloid M2-like activation in a STAT6 O-GlcNAcylation-dependent manner.Int Immunopharmacol, 131:111883, 2024.

2.Chen M#, Wang SN#, Chen YH#, Shen H, Chen L, Ding L, Tang QS, Yang ZY,Chen WQ*, Shen ZY*.Precision cardiac targeting: empowering curcumin therapy through smart exosome-mediated drug delivery inmyocardial infarction.Regen Biomater, 11:rbad108, 2023.

3.Ding L^#, Zhou WJ^#, Zhang J^#, Tang QS, Xiao WZ, Chen M, Shen ZY*,Chen WQ* Calming egress of inflammatory monocytes and related septic shock by therapeutic CCR2 silencing using macrophage-derived extracellular vesicles. Nanoscale, 14(13):4935-4945, 2022.（封面文章）

4.Zhou WJ^#, Jiang X^#, Tang QS^#, Ding L, Xiao WZ, Li JJ, Wu Y, Ruan HB, Shen ZY*, Chen WQ*. Glucosamine facilitates cardiac ischemic recovery via recruiting Ly6C^lowmonocytes in a STAT1 andO-GlcNAcylation dependent fashion. Clin Transl Med,12(3):e762, 2022.

5.Xiao WZ#, Chen M#, Zhou WJ, Ding L, Yang ZY, Shao LB, Li JJ,Chen WQ*, Shen ZY*. An immunometabolic patch facilitates mesenchymal stromal/stem cell therapy for myocardial infarction through a macrophage-dependent mechanism. Bioeng Transl Med,8(3):e10471, 2022.

6.Zhao P#, Zhou WJ#, Zhang YX#, Li JJ, Zhao Y, Pan LH, Shen ZY*,Chen WQ*, Hui J*. Aminooxyacetic acid attenuates post-infarct cardiac dysfunction by balancing macrophage polarization through modulating macrophage metabolism in mice. J Cell Mol Med, 24(4):2593-2609, 2020.

7.Wu JP#, Dong YY#, Teng XM#, Cheng MH, Shen ZY*,Chen WQ*. Follistatin-like 1 attenuates differentiation and survival of erythroid cells through Smad2/3 signaling. Biochem Biophys Res Commun, 466(4), 711-716, 2015.

第一作者文章

1.Feng JG#, Wu Y#,Chen WQ#, Li JJ, Wang XY, Chen Y, Yu YS*, Shen ZY*, Zhang YX*. Sustained release of bioactive IGF-1 from a silk fibroin microsphere-based injectable alginate hydrogel for the treatment of myocardial infarction. J Mater Chem B, 8(2):308-315, 2020.

2.Chen WQ, Shen ZY. Letter by Chen and Shen Regarding Article, “Exosomal microRNA transfer into macrophages mediates cellular postconditioning” Circulation, 137(2), 210-211, 2018.

3.Chen YQ#, Zhao YF#,Chen WQ#, Xie LC#, Zhao ZA, Yang JJ, Chen YH, Lei W*, Shen ZY*. MicroRNA-133 overexpression promotes the therapeutic efficacy of mesenchymal stem cells on acute myocardial infarction. Stem Cell Res Ther, 8(1):268, 2017.

4.Chen WQ#, Xia J#, Hu P#, Zhou F#, Chen YQ, Wu JP, Lei W, Shen ZY*. Follistatin-like 1 protects cardiomyoblasts from injury induced by sodium nitroprusside through modulating Akt and Smad1/5/9 signaling. Biochem Biophys Res Commun, 469(3), 418-423, 2016.

5.Chen WQ#, Wang SZ#, Xia J#, Huang Z, Tu X, Shen ZY*. Protein phosphatase 2A plays an important role in migration of bone marrow stroma cells. Mol Cell Biochem, 412(1-2), 173-180, 2016.

6.Chen WQ#, Huang Z#, Jiang X#, Li CF, Gao X*. Overexpression of myeloid differentiation protein-88 in mice induces mild cardiac dysfunction, but no deficit in heart morphology. Braz J Med Biol Res, 49(1), e4794, 2016.

7.Chen Y#, Zuo J#,Chen WQ#, Yang Z#, Zhang Y, Hua F, Shao L, Li J, Chen Y, Yu Y*, Shen Z*. The enhanced effect and underlying mechanisms of mesenchymal stem cells with IL-33 overexpression on myocardial infarction. Stem Cell Res Ther, 10(1):295, 2019.

8.Chen WQ, Gu PY, Jiang X, Ruan HB, Li CJ, Gao X*. Protein phosphatase 2A catalytic subunit α (PP2Acα) maintains survival of committed erythroid cells in fetal liver erythropoiesis through the STAT5 pathway. Am J Pathol,178(5), 2333-2343, 2011.

9.Chen WQ, Li CF, Jiang X, Ruan HB, Qi X, Liu L, Zhao QS, Gao X*. Over-expressing dominant negative MyD88 induces cardiac dysfunction in transgenic mice. Chinese Sci Bull, 55(31), 3569-3575, 2010.

合作文章

1.Wu Y, Chang T,Chen WQ, Wang X, Li J, Chen Y, Yu Y, Shen Z*, Yu Q*, Zhang Y*. Release of VEGF and BMP9 from injectable alginate based composite hydrogel for treatment of myocardial infarction. Bioact Mater, 6(2):520-528, 2020.

2.Yu Y, Qin N, Lu XA, Li J, Han X, Ni X, Ye L, Shen Z,Chen WQ, Zhao ZA*, Lei W*, Hu S*. Human embryonic stem cell-derived cardiomyocyte therapy in mouse permanent ischemia and ischemia-reperfusion models. Stem Cell Res Ther, 10(1):167, 2019.

3.Li H, Li J, Jiang X, Liu S, Liu Y,Chen W, Yang J, Zhang C, Zhang W. Melatonin enhances atherosclerotic plaque stability by inducing prolyl-4-hydroxylase α1 expression. J Hypertens, 37(5):964-971, 2019.

4.Li J, Liu S, Cao G, Sun Y,Chen WQ, Dong F, Xu J, Zhang C, Zhang W. Nicotine induces endothelial dysfunction and promotes atherosclerosis via GTPCH1. J Cell Mol Med, 22(11):5406-5417, 2018.

5.Huang Z, Ruan HB, Xian L,Chen WQ, Jiang SJ, Song AY, Wang QH, Shi PL, Gu XX, Gao X*. The stem cell factor/Kit signalling pathway regulates mitochondrial function and energy expenditure. Nat Commun, 5, 4282, 2014.

6. Huang Z, Ruan HB, Zhang ZD,Chen WQ, Lin ZY, Zeng H, Gao X*. Mutation in the first Ig-like domain of Kit leads to JAK2 activation and myeloproliferation in mice. Am J Pathol, 184(1), 122-132, 2014.

7. Chen YH#, Teng XM#,Chen WQ, Yang JJ, Yang ZY, Yu YS, Shen ZY*. Timing of transplantation of autologous bone marrow derived mesenchymal stem cells for treating myocardial infarction. Sci China Life Sci, 57(2), 195-200, 2014.

8.Jiang X, Zhou Y, Xian L,Chen WQ, Wu HW, Gao X*. The mutation in Chd7 causes misexpression of Bmp4 and developmental defects in telencephalic midline. Am J Pathol, 181(2), 626-641, 2012.

9.Zhou Y, Jiang X, Gu PY,Chen WQ, Zeng X, Gao X*. Gsdma3 mutation causes bulge stem cell depletion and alopecia mediated by skin inflammation. Am J Pathol, 180(2), 763-774, 2012.