题目：

Exploration of Ultrasound-Sensitive Biomaterials in Cancer Theranostics

作者：

Yuqi Yang^1,2,5, Huazheng Liang^2,3, Chun Tang⁴, Yuan Cheng^2,5, Liang Cheng^1,6

单位：

¹Institute of Functional Nano & Soft Materials (FUNSOM), Jiangsu Key Laboratory for Carbon-Based Functional Materials and Devices, Soochow University, Suzhou 215123 China

²Monash Suzhou Research Institute, Monash University, Suzhou 215000, China

³Australian Regenerative Medicine Institute, Clayton, VIC 3800, Australia

⁴Faculty of Civil Engineering and Mechanics, Jiangsu University, Zhenjiang 212013, China

⁵Department of Materials Science and Engineering, Monash University, Clayton, VIC 3800, Australia

⁶Macao Institute of Materials Science and Engineering, Macau University of Science and Technology, Taipa, Macau SAR 999078, China

摘要：

Cancer is a serious health problem to be solved. With the development of biomaterials, enhanced diagnostic and controllable therapeutic strategies for cancer have emerged, revealing encouraging results with a promising future. Due to its outstanding tissue penetration and controllability, along with a series of bioeffects on tissues, ultrasound (US), as a common medical technology, has been regarded as an effective tool against cancer, and its use has promoted the exploration of US-sensitive biomaterials. In this review, the bioeffects of US are first introduced and then the main US-sensitive biomaterials (containing cavitation nuclei, sonosensitizers, and US-responsive macromolecular systems) used to treat cancer, followed by a summary of several applications based on US-sensitive biomaterials, from diagnosis to therapy. Finally, the emerging challenges in this field that need to be overcome are highlighted. This review reports the progress of US-sensitive biomaterials, providing new possibilities in cancer theranostics and thus benefiting patients.

影响因子：

19.924

分区情况：

一区

链接：

https://onlinelibrary.wiley.com/doi/10.1002/adfm.202313454