武迪,www.优德88.cpm青年特聘教授、硕士生导师。2020年于北京大学获得博士学位,2020-2023年,在北京大学继续进行博士后研究。2023年11月起任www.优德88.cpm 转化医学研究院青年特聘教授。相关代表性工作以第一作者或共同一作发表于Nature Metabolism(2022,2023),Nature Communications等学术期刊。主持博士后特别资助(站中)项目并作为项目主要完成人参与多项国家自然科学基金、科技部重点研发计划项目等。
通讯地址:苏州市工业园区仁爱路199号www.优德88.cpm403幢3209室 邮编:215123
研究方向:
运用系统生物学方法探讨黏膜免疫反应及免疫细胞的代谢调控机制,及其在抗感染、自身免疫病等发生过程中的作用。
代表性研究论文:(#共同第一作者,*通讯作者)
1.Di Wu#, Luni Hu#, Mengwei Han#, Yichen Deng, Yime Zhang, Guanqun Ren, Xingyu Zhao, Zongxian Li, Peng Li, Yinlian Zhang, Shanwen Chen, Jun Li, Yanyan Shi, Jianxin Xue, Pengyuan Wang, Chao Zhong*. PD-1 signaling facilitates activation of lymphoid tissue inducer cells by restraining fatty acid oxidation.Nature Metabolism. 2022, 4 (7), 867-882.
2. Di Wu#, Zongxian Li#, Yime Zhang#, Yinlian Zhang#, Guanqun Ren#, Yanyu Zeng, Huiying Liu, Weiqiang Guan, Xingyu Zhao, Peng Li, Luni Hu, Zhiyuan Hou, Jingjing Gong, Jun Li, Wenfei Jin, Zeping Hu, Changtao Jiang, Houhua Li, Chao Zhong*. Proline uptake promotes activation of lymphoid tissue inducer cells to maintain gut homeostasis.Nature Metabolism. 2023, doi: 10.1038/s42255-023-00908-6.
3.Mengwei Han#,Luni Hu#,Di Wu#,Yime Zhang,Peng Li,Xingyu Zhao,Yanyu Zeng,Guanqun Ren,Zhiyuan Hou,Yanli Pang,Tongbiao Zhao,Chao Zhong*. IL-21R-STAT3 signalling initiates a differentiation program in uterine tissue-resident NK cells to support pregnancy.Nature Communications.2023, 14 (1), 7109.
4.Di Wu#,Yinlian Zhang#,Suwei Dong,Chao Zhong*.Biophysics Reports. 2021, 7(4), 326-340.
5.Di Wu#,Yinglu Li#,Kathy S Zhu,Haiying Wang,Wei-Guo Zhu*.Advances in Cellular Characterization of the Sirtuin Isoform, SIRT7.Frontiers in Endocrinology. 2018, 9:652.