杨乾磊、男、师资博士后
电子邮箱:qlyang@suda.edu.cn
通讯地址:苏州工业园区仁爱路199号www.优德88.cpm 一期医学楼医学部公共卫生学院,邮编215123
个人简介:
杨乾磊(QianleiYang),博士研究生学历,医学博士学位。
学习经历:
2018.09--2021.07www.优德88.cpm博士研究生卫生毒理学
2015.09--2018.07南京医科大学硕士研究生卫生毒理学
2010.09--2015.07南京医科大学康达学院大学本科预防医学
工作经历:
2017.10-2018.07,南京医科大学公共卫生学院,年级支部书记
2019.01.07-2019.01.22,日本大学药学部,访问学者
2021.08-至今,www.优德88.cpm 医学部公共卫生学院,师资博士后
目前学术任职:
中国生物物理学会自由基生物学与自由基医学分会青年委员
研究方向:
1.环境毒理学;
2.砷毒性氧化还原应激生物学研究
科研项目:
1.国家自然科学基金项目“砷致细胞恶性转化过程中ROS-自噬-凋亡的调控机制”(No.81872646),2019.01-2022-12,57万,参与。
2. 2018-2020年国家自然科学基金国际(地区)合作交流项目(与日本学术振兴会NSFC-JSPS)“砷致细胞恶性转化过程中二甲基化胂对转录因子Nrf2的作用研究”(No. 81811540034),2018.04-2020-12,20万,参与。
3.指导www.优德88.cpm2019年国家级大学生创新创业训练计划项目(201910285058)与江苏省大学生创新创业训练计划立项项目(201910285053Z):“Nrf2在砷致细胞恶性转化过程中对Warburg效应的调控作用”,已结题。
代表性论文(*通讯作者):
Jing Wu#, Yiping Ni#,Qianlei Yang#, Jiayuan Mao, Xuerui Zhu, Shasha Tao, Koichi Kato, Jie Zhang, Dapeng Wang*, Kenzo Yamanaka*, Yan An*,Long-term arsenite exposure decreases autophagy by increased release of Nrf2 in transformed human keratinocytes,Science of The Total Environment,2020, 734, 139425, https://doi.org/10.1016/j.scitotenv.2020.139425.(SCI1区,IF=6.551)
Jiayuan Mao#,Qianlei Yang#, Makoto Miyazawa, Motofumi Miura, Luna Wang, Haixuan Xia, Koichi Kato, Kenzo Yamanaka*, Yan An*,Possible differences in the mechanism of malignant transformation of HaCaT cells by arsenite and its dimethyl metabolites, particularly dimethylthioarsenics,Journal of Trace Elements in Medicine and Biology,2020, 61: 126544. doi: 10.1016/j.jtemb.2020.126544.(SCI 3区,IF=3.245)
Qianlei Yang#, Hanyi Deng#, Haixuan Xia#, Mengchuan Xu, Guotao Pan, JiayuanMao, Shasha Tao, Kenzo Yamanaka*& Yan An*.High NF-E2-related factor 2 expression predicts poor prognosis in patients with lung cancer: a meta-analysis of cohort studies.Free Radic Res.2019,1-9.(SCI 3区,IF=2.839)
Yang, Q.#,Zhu, Z.#, Wang, L., Xia, H., Mao, J., Wu, J., Kato, K., Li, H., Zhang, J., Yamanaka, K., An, Y*., 2019. The protective effect of silk fibroin on high glucose induced insulin resistance in HepG2 cells.Environmental toxicology and pharmacology,2019,69, 66-71. (SCI3区,IF=3.292)
Yang Q#, Cui Y#, Luo F, Liu X, Wang Q, Bai J, Dong F, Sun Q, Lu L, Xu H, Xue J, Chen C, Xiang Q, Liu Q*, Zhang Q.MicroRNA-191 viaIRS-1/Akt signaling pathway is involved in thehepatic insulin resistance induced by cigarette smoke extract.Environmental science and pollution research international.2018,25(23):22400-22407.(SCI3区,IF=2.914)
Sun, Qian#;Yang, Qianlei#; Xu, Hui; Xue, Junchao; Chen, Chao; Yang, Xingfen; Gao, Xiaohua; Liu, Qizhan*. miR-149 Negative Regulation of mafA Is Involved in the Arsenite-Induced Dysfunction of Insulin Synthesis and Secretion in Pancreatic Beta Cells.Toxicological Science,2018, 1–10.(SCI 2区,IF=3.564)
Chen, Chao#;Yang, Qianlei#; Yang, Ping; Wang, Dapeng; Luo, Fei; Liu, Xinlu; Liu, Qizhan*; Xue, Junchao; Xu, Hui; Lu, Jiachun; Zhang, Aihua. MicroRNA-191, regulated by HIF-2α, is involved in EMT and acquisition of a stem cell-like phenotype in arsenite-transformed human liver epithelial cells.Toxicology in vitro,2018, 48(128-136).(SCI 3区,IF=3.067)
承担的教学情况:
承担本科生教学课程:纳米世界漫谈
荣誉奖励:
杨乾磊,南京医科大学一等学业奖学金,2011年
杨乾磊,南京医科大学优秀共青团员,2012年
杨乾磊,www.优德88.cpm学业奖学金特等奖,2020年
杨乾磊,www.优德88.cpm优秀毕业研究生,2021年
杨乾磊,2021自由基生命科学峰会青年报告三等奖,2021年