姓名：信丽丽（1987.4-），女，河南周口人； 职称：副教授
1．学历
2008.09–2012.06华中科技大学博士研究生
2004.09–2008.06华中师范大学大学本科
2．工作经历和任职情况
2015.07-至今www.优德88.cpm 公共卫生学院副教授
2012.08–2015.06www.优德88.cpm 公共卫生学院 讲师
3．研究方向
环境毒理学，细胞对环境污染物的应激反应
4．承担课题情况
主持国家自然科学基金青年科学基金、江苏省基础研究计划（自然科学基金）-青年基金、中国博士后科学基金、江苏省高校自然www.优德88.cpm 面上项目各一项
5．发表论文情况
在Cell stress & Chaperone等学术期刊上发表SCI论文13篇，发表国内核心论文2篇，省级教育教学期刊论文两篇。
近年代表科研论文：
1) Xin LL, Li, XH, Deng HX, Kuang D, Dai XY, Huang SL, Wang F,He MA,R. William Currie, Wu TC. Development of stableHSPA1Apromoter-driven luciferase reporter HepG2 cells for assessing the toxicity of organic pollutants present in air. Cell Stress Chaperones, 2012 Sep; 17(5):567-576.
2) Xin LL, Wang JS, Guo SF, Wu YH, Li XH, Deng HX, Kuang D, Xiao W, Wu TC, Guo H. Organic extracts of coke oven emissions can induce genetic damage in metabolically competent HepG2 cells. Environ Toxicol Pharmacol, 2014 May; 37(3)946-953.
3) Xin LL, Wang JS, Wu YH, Guo SF. The development ofGADD45aluciferase reporter assays in human cells for assessing the genotoxicity of environmental pollutants. Toxicol Mech Methods, 2015 Feb; 25(2):136-142.
4) Xin LL, Wang JS, Wu YH, Guo SF, Tong J. Increased oxidative stress and activated heat shock proteins in human cell lines by silver nanoparticles. Hum Exp Toxicol, 2015 May; 34(3):315-323.
5) Xin LL, Wang JS, Fan GQ, Wu YH, Guo SF.Activation ofHSPA1Apromoter by environmental pollutants: an early and rapid response to cellular damage.Environ Toxicol Pharmacol, 2015 May; 39(3):1027-1033.
6) Xin LL, Wang JS, Fan GQ, Che BZ, Wu YH, Guo SF, Tong J.Oxidative stress and mitochondrial injury mediated cytotoxicity induced by silver nanoparticles in human A549 and HepG2 cells.Environ Toxicol, 2016 December; 31(12):1691-1699.
7) Xin LL, Lin Y, Wang AQ, Zhu W, Liang Y, Su XJ, Hong CJ, Wan JM, Wang YR, Tian HL. Cytogenetic evaluation for the genotoxicity of bisphenol-A in Chinese hamster ovary cells. Environ Toxicol Pharmacol, 2015 Sep; 40(2):524-529.
8) Xin LL, Wang JS, Zhang LW, Che BZ, Dong GZ, Fan GQ, Cheng KM.Development ofHSPA1Apromoter-driven luciferase reporter gene assays in human cells for assessing the oxidative damage induced by silver nanoparticles. Toxicol Appl Pharmacol, 2016 Aug; 304:9-17.
9)Xin LL, Wang JS, Fan GQ, Che BZ, Cheng KM, Dong GZ.Comparative oxidative stress elicited by nanosilver in stableHSPA1Apromoter-driven luciferase reporter HepG2 and A549 cells. Toxicol Res, 2016; 5:1306-1308.
10)Wang JS, Che BZ, Zhang LW, Dong GZ, Luo QL, Xin LL.Comparative genotoxicity of silver nanoparticles in human liver HepG2 and lung epithelial A549 cells. J Appl Toxicol, 2017; 37(4):495-501.
11) Che BZ, Luo QL, Zhai BZ, Fan GQ, Liu ZY, Cheng KM, Xin LL.Cytotoxicity and genotoxicity of nanosilver in stableGADD45αpromoter-driven luciferase reporter HepG2 and A549 cells. Environ Toxicol, 2017; 32(9):2203-2211.
12)信丽丽,李晓海,邓华欣,旷聃,戴霞云,黄素丽,王峰,何美安, Currie RW,邬堂春*, HSPA1A启动子荧光素酶报告基因HepG2细胞的构建及其在职业环境污染物毒性评估中的应用,中华劳动卫生职业病杂志,第30卷,第12期, 883-887页, 2012
13)信丽丽*,车碧众,武艳虎,郭思梵,焦炉逸散物和汽车尾气有机提取物对人肝癌细胞的遗传毒性作用,癌变畸变突变,第27卷,第4期, 299-303页, 2015
14) Li XH, Feng YY, Deng HX, Zhang WZ, Kuang D, Deng QF, Dai XY, Lin DF, Huang SL, Xin LL, He YF, Huang K, He MA, Zhang XM, Wu TC. The Dose–Response Decrease in Heart Rate Variability: Any Association with the Metabolites of Polycyclic Aromatic Hydrocarbons in Coke Oven Workers? PlOS One, 2012 Sep; 7(9):e44562.
15) Duan Y, Huang S, Yang J, Niu P, Gong Z, Liu X, Xin L, Currie RW, Wu T*. HspA1A facilitates DNA repair in human bronchial epithelia cells exposed to benzo[a]pyrene and interacts with casein kinase 2, Cell Stress and Chaperone, 2014 Mar; 19(2):2471-279.
6．教学工作
承担本科医学生环境卫生学、预防医学、健康与社会、环境污染与人体健康等课程的教学。参编教材：《辐射纳米医学与毒理学实验技术汇编》。
7．联系方式
联系电话：0512-65880074邮箱：llxin@suda.edu.cn