张增利
张增利(1967.5-),男,医学博士,教授,博士生导师,劳动卫生职业病学科负责人。苏州医学院公共卫生学院院长。
1.研究方向
职业流行病学、职业相关慢性病、维生素D与慢性病。
2.承担课题情况
完成三项国家自然科学基金(30570883、30972467、81372981)。在研一项国家自然科学基金。
3.发表论文和科研获奖情况
发表学术论文四十余篇;其中15篇被SCI检索。研究成果多次在国际学术会议上交流(会议论文8篇),并在大会上作口头发言四次,获31届ASBMR Young Investigator Award奖。参编英文教材一部,中文教材2部,主编专著一本,任一本专著副主编。
近3年代表论文:
1)Enhanced Radiosensitivity in 1,25-dihydroxyvitamin D3 deficiency Mice. Journal of Radiation Research. 2011;52(2): 215-9
2)Residential radon and lung cancer risk: an updated meta- analysis of case-control studies. Asian Pac J Cancer Prev. 2012;13(6):2459-65.
3)Partial Rescue of the Phenotype in 1α-hydroxylase Gene Knockout Mice by Vitamin D3 Injection. Endocrine Research. 2011, 36(3): 101-108
4) Carvacrol,aFood-Additive, Provides Neuroprotection on Focal Cerebral Ischemia/Reperfusion Injury in Mice. PLoS One. 2012;7(3):e33584.
5)Cadmium-induced renal tubular dysfunction in a group of welders. Occup Med (Lond). 2011, 61(4): 277-279
6)Proteome-wide inference of human endophilin 1-binding peptides. Protein Pept Lett. 2012 19(10):1094-102.
4.社会工作
参编大学生全国通用教材《职业卫生与职业医学》第七版、《环境与职业医学》杂志编委、《中国骨质疏松杂志》常务编委,江苏省毒理学会理事、中国免疫毒理学会委员、放射毒理学会委员。任中国骨质疏松学会常务委员,苏州市骨矿盐学会副主任委员。
5.学历
2002.09–2005.07www.优德88.cpm 放射医学 博士研究生
1998.09–2001.07苏州医学院预防医学系 硕士研究生
1983.09–1988.07山西医学院预防医学系 大学本科
6.工作经历和任职情况
2001.08–至今 www.优德88.cpm 公共卫生学院 讲师、副教授、教授
2003.02–2004.10加拿大McGill大学维多丽亚医院 访问学者
1988.07–1998.07乌鲁木齐铁路局卫生防疫站 医师、主治医师
7.联系方式
联系电话:65880056邮箱:zhangzengli@suda.edu.cn
Zengli Zhang, Ph.D.
Vice-Director, School of Public Health
Professor of Environmental Health
Professor of Nutrition
Department of Environmental Health, School of Public Health
Office/Address:
B402 Room, medical building 402
School of Public Health, Soochow University
199 Renai Road, Suzhou Jiangsu 215123
Phone: 512-6588-0056
Website address:
Email: zhangzengli@suda.edu.cn
BIOGRAPHY
Dr. Zengli Zhang's research focuses on non-classic actions of vitamin D, specifically mechanisms of vitamin d on diabetes and bone fracture at the cellular and molecular levels. Dr. Zhang is working on funded research programs focused on the basic cellular and molecular mechanisms of high dose vitamin d and low dose environmental heavy metals.
EDUCATION
PhD, 2001, Soochow University
BS, 1988, ShanXi Medical University
PUBLICATIONS:
1, Synergy of 1,25-dihydroxyvitamin D3 and carboplatin in growth suppression of SKOV-3 cells.Oncol Lett. 2014 Sep;8(3):1348-1354.
2,Serum activities of liver enzymes in workers exposed to sub-TLV levels of dimethylformamide.Int J Occup Med Environ Health. 2015;28(2):395-8.
3, Transplantation of bone marrow-derived mesenchymal stem cells rescues partially rachitic phenotypes induced by1,25-Dihydroxyvitamin D deficiency in mice.,Am J Transl Res,2016,8(10):4382~4393
4,Synergy of 1,25-dihydroxyvitamin D3 and carboplatin in growth suppression of SKOV-3 cells,Oncology Letters,2014.9.01,8(3):1348~1354
5, Vitamin D Deficiency in Relation to the Risk of Metabolic Syndrome in Middle-Aged and Elderly Patients with Type 2 Diabetes Mellitus.,J Nutr Sci Vitaminol (Tokyo),2016.01.01,62(4):213~219
6,1alpha,25(OH)(2)D(3) Suppresses the Migration of Ovarian Cancer SKOV-3 Cells through the Inhibition of Epithelial-Mesenchymal Transition.,Int J Mol Sci,2016.8.19,17(8)
7, Vitamin D Deficiency Increases the Risk of Gestational Diabetes Mellitus: A Meta-Analysis of Observational Studies.,Nutrients,2015.10.01,7(10):8366~8375
8,Upregulation of BTG1 enhances the radiation sensitivity of human breast cancer in vitro and in vivo,Oncology Reports,2015.12.01,34(6):3017~3024
9,Effect of Vitamin D Supplementation on the Level of Circulating High-Sensitivity C-Reactive Protein: A Meta-Analysis of Randomized Controlled Trials,Nutrients,2014.6.01,6(6):2206~2216
10,1alfa,25-dihydroxyvitamin D3 Attenuates TGF-b-Induced Pro-Fibrotic Effects in Human Lung Epithelial Cells through Inhibition of Epithelial-Mesenchymal Transition. Nutrients. 2017,9(9). pii: E980. doi: 10.3390/nu9090980.