段广新,副研究员
电话:0512-65880050传真:0512-65884380
电子邮箱:gxduan@suda.edu.cn
通讯地址:苏州工业园区仁爱路199号,邮编215123
个人简历:
段广新,www.优德88.cpm 医学部放射医学与防护学院副研究员,硕士生导师。2017博士年毕业于www.优德88.cpm ,放射医学专业;主要从事多功能化疗栓塞微球与放射栓塞微球的研发、多模态分子影像探针的设计、多功能纳米诊疗剂的制备及其在疾病中的应用研究、纳米探针与蛋白的相互作用及毒理学研究。共发表SCI论文30余篇,其中(共同)第一作者与(共同)通讯作者12篇。申请专利3项。
研究方向:
1.多功能化疗栓塞微球与放射栓塞微球的研发;
2.多功能纳米诊疗剂的制备及其在疾病中的应用研究;
3.多模态分子影像探针制备与应用。
科研项目:
1.国家自然基金青年项目,22006109,多功能90Y微球的构建及其在肝癌放射栓塞降期治疗中的应用研究,2021/01-2023/12,24万元,在研,主持
2.苏州医学创新应用研究项目,SKY2022104,多功能177Lu放射栓塞微球在中晚期肝癌治疗中的实验研究,2022/07-2025/06,5万,在研,主持
3.江苏省博士后基金,多功能90Y微球的构建及其在VX2肝癌模型放射栓塞治疗中的应用研究,2020/01-2022/12,2万元,在研,主持
4.苏州市科教兴卫青年科技项目,KJXW2017039,针对烧伤感染区域智能释放抗菌剂的水凝胶敷料研究,2018/01-2020/12,4万元,结题,主持
5.苏州市民生科技医疗卫生应用基础研究,sys2018087,新型g-C3N纳米材料的抗菌机制及在菌血症治疗中的应用探索,2018/07-2021/06,10万元,结题,主持
代表性论著:
1. Guangxin Duan#, Zhuxin Wei#, Jingyu Zhang, Xuexiao Li, Shuwang Wu, Jianfeng Zeng, Ximing Wang, Hong Zhang*, Ling Wen*, Mingyuan Gao, NIR-II Fluorescence Nanoprobe Based on Erbium for Fallopian Tube Diseases Diagnosis.Materials & Design,2023: 111726.
2. Xiuhua Yin#, Shitong Zhang#, Ling Wen#, Juan Su, Jian Huang,Guangxin Duan*, Zaixing Yang*,The Non-Monotonic Relationship between the Oxidation State of Graphene-based Materials and its Cell Membrane Damage Effects.ACS Applied Materials & Interface,2022, 14(26): 30306-30314.
3. Guangxin Duan#, Ling Wen#, Xingwei Sun, Zhuxin Wei, Ruixue Duan, Jiangfeng Zeng,Jiabin Cui, Chunyi Liu, Zepeng Yu, Xiaofang Xie, Mingyuan Gao*,Healing Diabetic Ulcers with MoO3−XNanodots Possessing Intrinsic ROS-Scavenging and Bacteria-Killing Capacities.Small,2021, 202101137.
4. Zhuxin Wei#,Guangxin Duan#, Baoxing Huang, Shanshan Qiu, Dandan Zhou, Jianfeng Zeng, Jiabin Cui, Chunhong Hu, Ximing Wang*, Ling Wen*, Mingyuan Gao, Rapidly liver-clearable rare-earth core–shell nanoprobe for dual-modal breast cancer imaging in the second near-infrared window.Journal of Nanobiotechnology,2021, 19, 369.
5. Qing Guo#,Ying Yang#,Lin Zhao,Jian Chen,Guangxin Duan*,Zaixing Yang*,Ruhong Zhou, Graphene oxide toxicity in W1118flies.Science of The Total Environment,2021,805,150302
6. Xuejie Xie#, Zhenyu Hou#,Guangxin Duan#, Shitong Zhang, Hong Zhou, Zaixing Yang*, Ruhong Zhou*. Boron nitride nanosheets elicit significant hemolytic activity via destruction of red blood cell membranes.Colloids and Surfaces B: Biointerfaces,2021, 203:111765
7. Xin Tian#,Zaixing Yang#,Guangxin Duan#, Anqing Wu, Zonglin Gu, Leili Zhang, Chunying Chen, Zhifang Chai, Cuicui Ge*, Ruhong Zhou*. Graphene Oxide Nanosheets Retard Cellular Migration via Disruption of Actin Cytoskeleton.Small,2017, 13(3): 201602133.
8. Guangxin Duan#, Seung-gu Kang#, Xin Tian, Jose Antonio Garate, Lin Zhao, Cuicui Ge*, Ruhong Zhou*. Protein corona mitigates the cytotoxicity of graphene oxide by reducing its physical interaction with cell membrane.Nanoscale,2015, 7(37): 15214-15224.