论文题目Relationship between Knee Alignment and T1rho Values of Articular Cartilage and Menisci in Patients with Knee Osteoarthritis

作者Ligong Wang*, Renata La Rocca Vieira, Leon D. Rybak, James Babb, Gregory Chang, Svetlana Krasnokutsky, Steven Abramson, Ravinder Regatte

期刊名、年、卷、期、页

European Journal of Radiology (Eur J Radiol) 2013; 82: 1946–1952.

摘要Objective: To assess the relationship between knee alignment and subregional T1rho values of the femorotibial cartilage and menisci in patients with mild (Kellgren-Lawrence grade 1) to moderate (KL3) osteoarthritis (OA) at 3T.

Materials and methods: 26 subjects with a clinical diagnosis of KL1-3 OA were included and subdivided into three subgroups: varus, valgus, and neutral. All subjects were evaluated on a 3T MR scanner. Mann-Whitney and Wilcoxon signed rank tests were performed to determine any statistically significant differences in subregional T1rho values of femorotibial cartilage and menisci among the three subgroups of KL1-3 OA patients.

Results: Medial femoral anterior cartilage subregion in varus group had significantly higher (p< 0.05) T1rho values than all cartilage subregions in valgus group. Medial tibial central cartilage subregion had significantly higher T1rho values (p< 0.05) than lateral tibial central cartilage subregion in varus group. The posterior horn of the medial meniscus in neutral group had significantly higher T1rho values (p< 0.0029) than all meniscus subregions in valgus group.

Conclusion: There exists some degree of association between knee alignment and subregional T1rho ?values of femorotibial cartilage and menisci in patients with clinical OA.

影响因子：2.512

分区情况：3 - 4区(大于2)

链接：http://www.sciencedirect.com/science/article/pii/S0720048X13002556