曾剑峰特聘教授,博士生导师
电子邮箱:jfzeng@suda.edu.cn
通讯地址:苏州工业园区仁爱路199号, 邮编215123
办公电话:0512-65882542
个人简历:
曾剑峰,www.优德88.cpm 特聘教授,国家优秀青年科学基金获得者。2008年本科毕业于中南大学化学工程与工艺专业,同年加入中国科学院化学研究所高明远研究员课题组硕博连读。2014年获得物理化学理学博士学位,毕业后进入www.优德88.cpm 分子影像与核医学研究中心。截至目前,主持国家级项目4项、省部级项目4项,在Adv. Mater.、J. Am. Chem. Soc.、Angew. Chem.Int. Ed.、ACS Nano、Biomaterials等学术刊物上发表学术论文60多篇,被引4000多次,申请发明专利10项。
学习经历:
2004-2008年中南大学化学工程与工艺专业本科
2008-2014年中国科学院化学研究所物理化学专业博士(导师:高明远)
研究方向:
w 分子影像与纳米医学
w 核医学药物
w 转化医学
科研项目:
1.国家自然科学基金优秀青年基金项目,82222033,纳米分子影像及活体成像,2023.01-2025.12,主持
2. 国家自然科学基金面上项目,82172003,易损性动脉粥样硬化斑块的早期预警及动态可视化评估,2022.01-2025.12,主持
3. 国家重点研发计划“数字诊疗装备”重点专项课题,2016YFC0101201,高灵敏肿瘤多模态纳米分子影像探针,2016.07-2018.12,主持
4.国家重点研发计划“纳米科技”重点专项,2018YFA0208800,新型纳米氧化铁磁共振造影剂的宏量制备及临床转化研究,2018.05-2023.04,参与(项目PI)
5. 国家自然科学基金青年科学基金项目,21503141,高灵敏度化学交换饱和转移磁共振分子影像探针的构建及应用,2016.01-2018.12,主持
6. 江苏省高等学校自然www.优德88.cpm 重大项目,20KJA150006,磁共振/核医学双模态纳米分子影像探针应用基础研究,2020.10-2023.09,主持
7. 江苏省自然科学基金面上项目,BK20191418,可肾代谢氧化铁纳米磁共振造影剂的设计、合成及应用,2019.07-2022.06,主持
8.苏州市重点产业技术创新项目,新型纳米氧化铁静脉补铁剂开发,2020.07-2023.06,主持
9. 中国博士后科学基金第9批特别资助,2016T90489,配位聚合物纳米颗粒诊疗一体化探针的构建及应用,2016.07-2018.06,主持
10. 中国博士后科学基金第57批面上资助(一等),2015M570472,高灵敏度智能化磁共振分子影像探针的构建及应用,2015.07-2017.06,主持
11.北京分子科学国家实验室开放课题,20140165,高灵敏度智能化磁共振分子影像探针,2015.01-2016.12,主持
代表性论文:
1.
Anchoring Group Mediated Radiolabeling of Inorganic Nanoparticles - A Universal Method for Constructing Nuclear Medicine Imaging Nanoprobes
Jianxian Ge, Lei Chen, Baoxing Huang, Yun Gao, Dandan Zhou, Yi Zhou, Can Chen, Ling Wen, Qing Li,Jianfeng Zeng*, Zhiyuan Zhong, and Mingyuan Gao*
ACS Appl. Mater. Inter.,2022,DOI: 10.1021/acsami.1c23907.
2.
Anchoring Group Mediated Radiolabeling for Achieving Robust Nano-Imaging Probes
Lei Chen, Jianxian Ge, Baoxing Huang, Dandan Zhou, Gang Huang,Jianfeng Zeng*, and Mingyuan Gao
Small,2021,202104977
3.
Ultrasmall Superparamagnetic Iron Oxide Nanoparticles: A Next Generation Contrast Agent for Magnetic Resonance Imaging
Can Chen#, Jianxian Ge#, Yun Gao, Lei Chen, Jiabin Cui,Jianfeng Zeng*, and Mingyuan Gao*
WIREs Nanomed. Nanobi.,2021.DOI: 10.1002/wnan.1740
4.
Quantitative Mapping of Glutathione within Intracranial Tumors through Interlocked MRI Signals of a Responsive Nanoprobe
Peisen Zhang#,Jianfeng Zeng#, Yingying Li, Chen Yang, Junli Meng, Yi Hou,* and Mingyuan Gao*
Angew. Chem. Int. Edit.,2021, 60(15), 8130-8138.
5.
Radiolabeling nanomaterials for multimodality imaging: New insights into nuclear medicine and cancer diagnosis
Jianxian Ge, Qianyi Zhang,Jianfeng Zeng*, Zi Gu*, Mingyuan Gao
Biomaterials,2020,228, 119553.
6.
Self-Assembled Hybrid Nanocomposites for Multimodal Imaging-Guided Photothermal Therapy of Lymph Node Metastasis
Wu Cai#, Guohua Fan#, Hui Zhou#, Lei Chen, Jianxian Ge, Baoxing Huang, Dandan Zhou,Jianfeng Zeng,* Qingqing Miao,* and Chunhong Hu*
ACS Appl. Mater. Inter.,2020, 12(44),49407-49415.
7.
A Dual-Modal Molecular Probe for Near-Infrared Fluorescence and Photoacoustic Imaging of Peroxynitrite
Jianjian Zhang, Xu Zhen,Jianfeng Zeng*, and Kanyi Pu*
Anal. Chem.,2018,90(15), 9301-9307.
8.
Dual-Ratiometric Target-Triggered Fluorescent Probe for Simultaneous Quantitative Visualization of Tumor Microenvironment Protease Activity and pH in vivo
Tiancong Ma#, Yi Hou#,Jianfeng Zeng#, Chunyan Liu, Peisen Zhang, Lihong Jing, Dihua Shangguan, and Mingyuan Gao*
J. Am. Chem. Soc.,2018,140(1), 211-218.
9.
Enhancing Both Biodegradability and Efficacy of Semiconducting Polymer Nanoparticles for Photoacoustic Imaging and Photothermal Therapy
Yan Lyu#,Jianfeng Zeng#, Yuyan Jiang, Xu Zhen, Ting Wang, Shanshan Qiu, Xin Lou*, Mingyuan Gao, Kanyi Pu*
ACS Nano,2018,12(2), 1801-1810.
10.
Biodegradable Nano-agents with Short Biological Half-life for SPECT/PAI/MRI Multimodality Imaging and PTT Therapy of Tumors
Lei Chen#, Jaiyao Chen#, Shanshan Qiu, Ling Wen, Yan Wu, Yi Hou, Yong Wang,Jianfeng Zeng*, Yuan Feng, Zhen Li, Hong Shan*, and Mingyuan Gao*
Small,2018,14(4), 1702700.
11.
pH-Responsive Fe(III)-Gallic-Acid Nanoparticles for In-Vivo Photoacoustic Imaging Guided Photothermal Therapy
Jianfeng Zeng#, Ming Cheng#, Yong Wang, Ling Wen, Ling Chen, Zhen Li*, Yongyou Wu*, Mingyuan Gao*, Zhifang Chai
Adv. Healthc. Mater.,2016,5(7), 772-780.
12.
A Self-Assembled Albumin-Based Nanoprobe for In Vivo Ratiometric Photoacoustic pH Imaging
Qian Chen, Xiaodong Liu, Jiawen Chen,Jianfeng Zeng*, Zhenping Cheng, Zhuang Liu*
Adv. Mater.,2015,27(43), 6820–6827.
13.
Anchoring Group Effects of Surface Ligand on Magnetic Properties of Fe3O4Nanoparticles: Towards High Performance MRI Contrast Agents
Jianfeng Zeng, Lihong Jing, Yi Hou, Mingxia Jiao, Ruirui Qiao, Qiaojuan Jia, Chunyan Liu, Fang Fang, Hao Lei, Mingyuan Gao*
Adv. Mater.,2014,26(17), 2694-2698.
荣誉奖励:
2022年国家优秀青年科学基金
2021年江苏省333高层次人才(第三层次)
2020年教育部高等学校www.优德88.cpm 优秀成果奖(科学技术)一等奖(排名第5)
2019年苏州市医学会医学科学技术一等奖(排名第4)
2019年中国医药生物技术协会造影技术分会委员
2019年日本国立放射线医学综合研究所的客座研究员
2017年www.优德88.cpm 优秀青年学者
2016年苏州市高等院校、科研院所紧缺高层次人才