朱巍,副教授

电话:13912603156

   传真:0512-65884380

   电子邮箱:zwhh1838@163.com

   通讯地址:苏州工业园区仁爱路199,邮编215123

个人简介:

1993年从苏州医学院放射医学系毕业并留校工作,历任放射医学系助教、讲师、副教授,博士。参加工作以来,主要从事辐射遗传学、辐射生物剂量估算、肿瘤放射生物学的教学、科研工作。2001年赴德国慕尼黑国家GSF放射生物实验室,2003年赴美国西南医学中心辐射遗传实验室从事FISH等相关研究。主持国家自然科学基金两项。参与多项国家自然基金、科技部重大专项、省高校基金的研究,发表科研及教学论文多篇。

研究方向:

   辐射损伤生物标志物,辐射生物剂量评估,肿瘤放疗增敏

科研项目:

国家自然科学基金“新抗肿瘤药物N544的动物实验研究”(项目批准号:30672435)2007.12009.12)项目负责人28

   国家自然科学基金PPARα和Nrf2共调控四氢生物蝶呤合成途径在放射性皮肤损伤防治中的作用和机制研究”(项目批准号:81573080)2016.12019.12)项目负责人65

代表性论著:

1.Xue J,Zhu W,Song J, Jiao Y, Luo J, Yu C, Zhou J, Wu J, Chen M, Ding WQ, Cao J*, Zhang S*. Activation of PPARα by clofibrate sensitizes pancreatic cancer cells to radiation through the Wnt/β-catenin pathway. Oncogene. 2018;37(7):953-962.

2.Yu C(#)Jiao Y(#)Xue J(#)Zhang QYang HXing LChen GWu JZhu W(*)Cao J(*)Metformin Sensitizes Non-small Cell Lung Cancer Cells to an Epigallocatechin-3-Gallate (EGCG) Treatment by Suppressing the Nrf2/HO-1 Signaling PathwayInt J Biol Sci20172

3.Wei Zhu,Jing XU,Yangyang GE,Han CAO,Xin GE,Judong LUO,Jiao XUE,Hongying YANG,Shuyu ZHANG,Jianping CAO; Epigallocatechin-3-gallate (EGCG) protects skin cells from ionizing radiation via heme oxygenase-1 (HO-1) overexpression, Journal of Radiation Research, 2014, 55, 1056–1065

4. Judong Luo1,Wei Zhu, Yiting Tang1, Han Cao1, Yuanyuan Zhou1, Rong Ji1, Xifa Zhou2, Zhongkai, ?Lu2Hongying Yang1, Shuyu Zhang1 and Jianping CaoArtemisinin derivative artesunate induces radiosensitivity in cervical cancer cells in vitro and in vivo. Radiation Oncology 2014, 9:84

5. RAN ZHU, SHI-TAO ZOU, JIAN-MEI WAN, WEI LI, XIN-LI LI andWei Zhu; BTG1 inhibits breast cancer cell growth through induction of cell cycle arrest and apoptosis, ?ONCOLOGY REPORTS 30: 2137-2144, 2013

6.YANG JIAO,CHANG LIU, FENG-MEI CUI,JIA-YING XU, JIAN TONG,XIAO-FEI QI, LI-LI WANGandWei Zhu; Long intergenic non-coding RNA induced by X-ray irradiation regulates DNA damage response signaling in the human ?bronchial epithelial BEAS-2B cell line, Oncology Letters,.20159(1):169-176.

荣誉奖励:

 苏州市科技进步一等奖,2009年度,排名第2

课程教学及招生信息:

⒈医学遗传学

⒉辐射遗传学