冯良珠,博士,教授
教育经历:
2010/09-2015/06,www.优德88.cpm ,功能纳米与软物质研究院,理学博士
2013/09-2014/10,美国佐治亚理工学院,生物医学工程系,联合培养博士(CSC资助)
2006/09-2010/06,www.优德88.cpm ,基础医学与生物科学学院,理学学士
工作经历
2015/10-2016/10,澳门大学,中华医药研究院,博士后
2016/11-2018/06,www.优德88.cpm ,功能纳米与软物质研究院,助理研究员
2018/07-2022/06,www.优德88.cpm ,功能纳米与软物质研究院,副研究员/www.优德88.cpm 优秀青年学者
2022/07-至今www.优德88.cpm ,功能纳米与软物质研究院,研究员/www.优德88.cpm 优秀青年学者
联系方式
江苏省苏州市工业园区仁爱路199号,910楼401室
邮箱:lzfeng@suda.edu.cn
电话86-512-65880927
代表性研究成果:
2010年以来,冯良珠博士的研究兴趣集中在功能化纳米药物载体/生物材料的构建、肿瘤微环境调节与新型肿瘤联合治疗等方面。迄今在Science Advances, Nature Communications, Chem, J. Am. Chem. Soc., Adv. Mater.等高水平学术期刊上发表论文110余篇,文章的总他引16600余次,SCI H-index为58;两次入选美国美国科睿唯安公布的“全球高被引科学家名单”(Highly Cited Researchers,交叉领域,2019、2021年);主持/参与国自然面上项目、科技部重点研发计划,江苏省优秀青年基金等项目资助。目前,担任Nature Communication, ACS Nano, Nano Letters, Biomaterials, Journal of Controlled Release等多个生物材料类学术期刊的特邀审稿人。
主要研究方向:
1.仿生纳米载体与肿瘤靶向药物递送
2.生物催化材料与肿瘤生物催化治疗
3.金属离子载体与肿瘤离子干扰治疗
4.肿瘤微环境调控与序贯性联合治疗
荣誉奖励
2022江苏省优秀青年基金
2021科睿唯安-全球高被引科学家(交叉学科)
2019科睿唯安-全球高被引科学家(交叉学科)
2016江苏省科学技术一等奖 (排名第五)
学术兼职
Young Editorial Board Members, BMEMat (2022-)
ECR board member, Materials Today Bio (IF = 10.761, Q1, 2022-)
Editorial board member, Nanomaterials (IF = 5.719, Q1, 2021- )
招生方向:
本课题组热忱欢迎有志从事科研工作的本科生、硕士研究生、博士研究生以及交流生到课题组学习工作。招生方向包括化学、材料学、生物化学与分子生物学、免疫学和生物医学工程等。有疑问请随时邮件联系lzfeng@suda.edu.cn。
招聘信息:
根据课题组发展需要,现拟招聘1-2名从事高分子合成、医学免疫学、生物医学工程等相关研究方向的博士后研究人员,待遇优厚。有意者请发送简历至lzfeng@suda.edu.cn。
代表性论文:
[20] Yujie Zhu, Zhijuan Yang, Zijian Pan, Yu Hao, Chunjie Wang, Ziliang Dong, Quguang Li, Yikai Han, Longlong Tian,Liangzhu Feng*, Zhuang Liu* Metallo-alginate hydrogel can potentiate microwave tumor ablation for synergistic cancer treatment.Sci. Adv., 2022, 8(31), abo5285
[19]Yu Hao, Lei Zhang, Ziliang Dong, Chunjie Wang, Yu Chao, Dongxu Zhao, Yujie Zhu, Zhijuan Yang, Nailin Yang, Yikai Han,Liangzhu Feng*, Zhuang Liu*, Percutaneous implantation of ethanol fueled catalytic hydrogel suppresses tumor growth by triggering ferroptosis,Mater. Today, 2022, 55, 7-20.
[18] Zhijuan Yang, Yujie Zhu, Ziliang Dong, Yu Hao, Chunjie Wang, Quguang Li, Yumin Wu,Liangzhu Feng*, Zhuang Liu*, Engineering bioluminescent bacteria to boost photodynamic therapy and systemic anti-tumor immunity for synergistic cancer treatment.Biomaterials, 2022, 281, 121332.
[17] Chunjie Wang, Ziliang Dong, Yu Hao, Yujie Zhu, Jing Ni, Quguang Li, Bo Liu, Yikai Han, Zhijuan Yang, Jianmei Wan, Kai Yang, Zhuang Liu*,Liangzhu Feng*, Coordination Polymer-Coated CaCO3Reinforces Radiotherapy by Reprogramming the Immunosuppressive Metabolic Microenvironment.Adv. Mater., 2022, 34(3), 2106520.
[16] Zhijuan Yang, Yujie Zhu, Ziliang Dong, Wei Li, Nailin Yang, Xianwen Wang,Liangzhu Feng*, Zhuang Liu*, “Tumor-killing nanoreactors fueled by tumor debris can enhance radiofrequency ablation therapy and boost antitumor immune responses”Nat. Commun.2021, 12, 4299.
[15] Quguang Li, Ziliang Dong, Meiwan Chen* andLiangzhu Feng*, Phenolic molecules constructed nanomedicine for innovative cancer treatment.Coord. Chem. Rev., 2021, 439.
[14] Yujie Zhu, Zhijuan Yang, Ziliang Dong, Yimou Gong, Yu Hao, Longlong Tian, Xianzhu Yang, Zhuang Liu*,Liangzhu Feng*, “CaCO3-Assisted Preparation of pH-Responsive Immune-Modulating Nanoparticles for Augmented Chemo-Immunotherapy”Nano-Micro Lett.2021, 13(1),1-18.
[13] Ziliang Dong, Yu Hao, Quguang Li, Zhijuan Yang, Yujie Zhu, Zhuang Liu,Liangzhu Feng*, “Metal-polyphenol-network coated CaCO3as pH-responsive nanocarriers to enable effective intratumoral penetration and reversal of multidrug resistance for augmented cancer treatments”Nano Res. 2020, 13, 3057–3067.
[12] Ziliang Dong,Liangzhu Feng*, Yu Hao, Quguang Li, Muchao Chen, Zhijuan Yang, He Zhao, Zhuang Liu*, “Synthesis of CaCO3-Based Nanomedicine for Enhanced Sonodynamic Therapy via Amplification of Tumor Oxidative Stress”Chem2020, 6(6), 1391-1407.
[11] Ziliang Dong,Liangzhu Feng*, Yu Chao, Yu Hao, Muchao Chen, Fei Gong, Xiao Han, Rui Zhang, Liang Cheng,Zhuang Liu*, “Amplification of Tumor Oxidative Stresses with Liposomal Fenton Catalyst and Glutathione Inhibitor for Enhanced Cancer Chemotherapy and Radiotherapy”Nano Lett.2019, 19, 805-815
[10] Ziliang Dong,Liangzhu Feng*, Yu Hao, Muchao Chen, Min Gao, Yu Chao, He Zhao, Wenwen Zhu, Jingjing Liu, Chao Liang, Qiao Zhang, and Zhuang Liu*, Synthesis of Hollow Biomineralized CaCO3-Polydopamine Nanoparticles for Multimodal Imaging-Guided Cancer Photodynamic Therapy with Reduced Skin Photosensitivity,J. Am. Chem. Soc., 2018, 140, 2165–2178
[9] Danlei Tao,Liangzhu Feng*, Yu Chao, Chao Liang, Xuejiao Song, Hairong Wang, Kai Yang, Zhuang Liu*, “Covalent Organic Polymers Based on Fluorinated Porphyrin as Oxygen Nano-Shuttles for Tumor Hypoxia Relief and Enhanced Photodynamic Therapy”Adv. Funct. Mater.2018, 28, 1804901
[8]Liangzhu Feng#, Ziliang Dong#, Chao Liang, Muchao Chen, Danlei Tao, Liang Cheng, Kai Yang, Zhuang Liu*, “Iridium Nanocrystals Encapsulated Liposomes as Near-Infrared Light Controllable Nanozymes for Enhanced Cancer Radiotherapy”Biomaterials, 2018, 181, 81-91
[7]Yicheng Zhang,Liangzhu Feng*, Jun Wang, Danlei Tao, Chao Liang, Liang Cheng, Erhong Hao*, Zhuang Liu*, “Surfactant‐Stripped Micelles of Near Infrared Dye and Paclitaxel for Photoacoustic Imaging Guided Photothermal‐Chemotherapy”Small, 2018, 14, 1802991
[6]Liangzhu Feng, Ziliang Dong, Danlei Tao, Yicheng Zhang, Zhuang Liu*, The acidic tumor microenvironment: a target for smart cancer nano-theranostics,Natl. Sci. Rev., 2018, 5, 269-286,
[5]Liangzhu Feng, Danlei Tao, Ziliang Dong, Qian Chen, Yu Chao, Zhuang Liu*, Meiwan Chen*, Near-infrared Light Activation of Quenched Liposomal Ce6 for Synergistic Cancer Phototherapy with Effective Skin Protection,Biomaterials, 2017, 127, 13-24
[4]Liangzhu Feng, Min Gao, Danlei Tao, Qian Chen, Hairong Wang, Ziliang Dong, Meiwan Chen,* and Zhuang Liu*, Cisplatin-Prodrug-Constructed Liposomes as a Versatile Theranostic Nanoplatform for Bimodal Imaging Guided Combination Cancer Therapy,Adv. Funct. Mater., 2016, 26, 2207-2217
[3] Ziliang Dong,Liangzhu Feng*, Wenwen Zhu, Xiaoqi Sun, Min Gao, He Zhao, Yu Chao, Zhuang Liu*, CaCO3Nanoparticles as an Ultra-sensitive Tumor-pH-Responsive Nanoplatform Enabling Real-Time Drug Release Monitoring and Cancer Combination Therapy,Biomaterials, 2016, 110, 60-70
[2]Liangzhu Feng#, Xianzhu Yang#, Xiaoze Shi, Xiaofang Tan, Rui Peng, Jun Wang*, Zhuang Liu*, Polyethylene glycol and polyethylenimine dual functionalized nano-graphene oxide for photothermally enhanced gene delivery,Small, 2013, 9 (11), 1989-1997
[1]Liangzhu Feng, Shuai Zhang, Zhuang Liu*, Graphene based gene transfection,Nanoscale, 2011, 3 (3), 1252-1257
发表论文列表:
https://scholar.google.com/citations?user=MkQwgDsAAAAJ&hl=en
课题组网页:http://nano.suda.edu.cn/lz/flzls/list.htm
责任编辑:杨娟