杨恺
时间:2024-06-05作者:浏览次数:29


杨恺，www.优德88.cpm 特聘教授/博士生导师，国家优青，江苏省“333高层次人才”，苏州市高等院校、科研院所紧缺高层次人才


研究方向：

主要从事细胞生物物理和生命软物质材料方面的研究，致力于从物理的角度，以生物界面为研究核心，发展先进的理论模拟与实验结合的研究方法，揭示纳米材料与生物界面的相互作用分子机制，设计开发先进生物医药用材料。


代表作：

  1. JF Wu, C Xu, ZF Ye, HB Chen#, YP Wang*,K Yang*, Bing Yuan*, Transition between different diffusion modes of individual lipids during the membrane-specific action of As-CATH4 Peptides,Small, 2023, 19，202301713.

  2. ZX Deng, X You, Z Lin, XW Dong, B Yuan*,K Yang*,Membrane-active peptides attack cell membranes in a lipid-regulated curvature-generating mode,J. Phys. Chem. Lett., 2023, 14,6422-6430.

  3. L Ou, H Chen, B Yuan*,K Yang*, Membrane-specific binding of 4 nm lipid nanoparticles mediated by an entropy-driven interaction mechanism,ACS Nano, 2022, 16, 18090-18100.

  4. YS Wei, HB Chen, YX Li, KJ He,K Yang*, HB Pang*, Synergistic entry of individual nanoparticles into mammalian cells driven by free energy decline and regulated by their sizes,ACS Nano, 2022, 16, 4, 5885–5897.

  5. WD Ma, XK Jiang, YJ Dou, ZH Zhang, J Li, B Yuan,K Yang.Biophysical impact of lipid A modification caused by mobile colistin resistance gene on bacterial outer membranes,J. Phys. Chem. Lett,2021,12,11629-11635.

  6. C Xu, WD Ma, K Wang, KJ He, ZL Chen, JJ Liu,K Yang*, B Yuan*,Correlation between single molecular dynamics and biological functions of antimicrobial peptide melittin,J. Phys. Chem. Lett., 2021, 11,4834–4841.

  7. X Lu,JJ Liu, L Gou, JL Li, B Yuan*,K Yang*, and YQ Ma*, Designing Melittin-Graphene Hybrid Complexes for Enhanced Antibacterial Activity.Adv. Healthcare Mater., 2019,1801521.

  8. QJ Ji, B Yuan, XM Lu,K Yang*, and YQ Ma*. Controlling the Nanoscale Rotational Behaviors of Nanoparticles on the Cell Membranes: A Computational Model.Small, 2016, 12, 1140-1146

  9. Ye Li, TT Yue,K Yang*, XR Zhang, Molecular modelling of the relationship between nanoparticle shape anisotropy and endocytosis kinetics.Biomaterials, 2012, 33, 4965-4973.

  10. K Yang, YQ Ma, Computer simulation of the translocation of nanoparticles with different shapes across a lipid bilayer,Nat. Nanotechnol., 2010, 5, 579-583.