Chen Gaojian

Professor Gaojian CHEN

PhD, FRSC

Emailgchen@suda.edu.cn




Education and Academic Experience

Gaojian Chen received his B.S. and M. Sc. from Soochow University in 2000 and 2003, and his Ph.D. from the University of Warwick in 2007. He worked as a postdoc research fellow at the University of New South Wales (2007-2009) and the Chinese University of Hong Kong (2010-2012). His primary appointment is at the College of Chemistry, Chemical Engineering and Materials Science, he is also a faculty member of Center for Soft Condensed Matter Physics and Interdisciplinary Research at Soochow University.

Research interests

Polymer synthesis and application

(1) Synthesis and application of glycopolymers

(2) Polymer synthesis (sunlight controlled polymerization, live template polymerization etc.)

(3) Surface modification (surface initiated polymerization, cell surface engineering etc.)

Selected publications

Articles:

1. Yu, L., Feng, R., Zhu, L., Hao, Q., Chu, J., Gu, Y., Luo, Y., Zhang, Z., Chen, G., Chen, H. (2020). Promoting the activation of T cells with glycopolymer-modified dendritic cells by enhancing cell interactions.Science Advances, 6(47), eabb6595.

2. Hu, J., Gu, Y., Liu, M., Zhang, W., Chen, H., Chen, G. (2020). Bacteria mimics bearing carbohydrates, oligodeoxynucleotides and designed shapes.Chemical Communications, 56(74), 10887–10889.

3. Xu, F., Jing, W., Chen, G., Zhang, Z. (2020). Polymerization in Shear Flow: From Bowl-Shaped Glyco-Microcarriers to Self-Propelled Micromotors.ACS Macro Letters, 9–13.

4. Zheng, Y., Luo, Y., Feng, K., Zhang, W., Chen, G. (2019). High Throughput Screening of Glycopolymers: Balance between Cytotoxicity and Antibacterial Property.ACS Macro Letters, 8(3), 326–330.

5. Liu, Q., Jiang, S., Liu, B., Yu, Y., Zhao, Z.-A., Wang, C., Liu, Z., Chen, G., Chen, H. (2019). Take Immune Cells Back on Track: Glycopolymer-Engineered Tumor Cells for Triggering Immune Response.ACS Macro Letters, 8(4), 337–344.

6. Luo, Y., Gu, Y., Feng, R., Brash, J., Eissa, A. M., Haddleton, D. M., Chen, G., Chen, H. (2019). Synthesis of glycopolymers with specificity for bacterial strains via bacteria-guided polymerization.Chemical Science, 10(20), 5251–5257.

Book Chapters:

1. Feng, K., Hu, J., & Chen, G. (2021).Surface Immobilized Glycopolymers. In J. Barchi (Ed.),Comprehensive Glycoscience(2nd ed., 346–369). Elsevier.

2. Zhang, W., Chen, K. & Chen, G. (2016) Thiol-Based “Click” Chemistry for Macromolecular Architecture Design, in S. Chandrasekaran (Ed.),Click Reactions in Organic Synthesis(255-285). Wiley-VCH.

3. Li, X., Zhang, W., & Chen, G. (2016). Synthesis of Non-spherical Glycopolymer-Decorated Nanoparticles: Combing Thiol-ene with Catecholic Chemistry. In X. L. Sun (Ed.),Macro-Glycoligands. Methods in Molecular Biology(149–155). Springer.

4. Zhao, Y., Chen, G. & Chen G. (2015). Self-Assembly of Glycopolymers: From Nano-Objects to Hydrogels. In C. R. Becer & L. Hartmann (Ed.),Glycopolymer Code: Synthesis of Glycopolymers and their Applications(178-195). The Royal Society of Chemistry.

5. Pearson, S., Chen, G., & Stenzel, M. H. (2011). Synthesis of Glycopolymers. In R. Narain (Ed.),Engineered Carbohydrate-Based Materialsfor Biomedical Applications(1–118). John Wiley & Sons.