李杰
姓名:李杰
职称:教授

部门:化学学院
联系方式:

Email:jjackli@suda.edu.cn

01. 2020-至今教授,www.优德88.cpm材料与化学化工学部,苏州,江苏

10. 2017- 11.2019慕尼黑大学化学与药学院博士后研究员,慕尼黑,德国;(合作导师:Prof. Dr. Paul Knochel)

10. 2015- 10. 2017特聘研究员,江南大学药学院,无锡,江苏

08. 2015- 10. 2015访问学者,中国医学科学院药物研究所药物化学室(肖志艳研究员)

11. 2011- 07. 2015哥廷根大学有机化学与分子生物化学系博士,哥廷根,德国;(博士学位summa cum laude;合作导师:Prof. Dr. Lutz Ackermann).

08. 2009- 10. 2011中国医学科学院药物研究所药物化学室(硕士交换生;导师:肖志艳研究员).

09. 2008- 07. 2009沈阳药科大学(天然)药物化学系硕士(导师:华会明教授).

09. 2004- 06. 2008(学士学位).天津商业大学制药工程系


学历及学术经历:2012年至今以一作或通讯作者在J. Am. Chem. Soc., Angew. Chem. Int. Ed., ACS Catal., Org. Lett., Adv. Synth. Catal., Chem. Eur. J., J. Org. Chem.,等期刊上发表学术论文20余篇;入选2016年江苏省双创人才;目前完成国家自然科学基金青年项目一项、江苏省自然科学基金青年基金一项。

研究领域: 金属 有机化学 & 药物化学
代表性论文(*通讯作者):

1.Z. Zhang, L. Liu, Y. Wang, Y. Zhang,J. Li*,Electrophilic Amination with Anthranils through Cobalt(III)-Catalyzed C(sp3)H Activation.Synthesis2020,DOI: 10.1055/s-0039-1690087.

2.J. Li*, Q. Ren, X. Cheng, K. Karaghiosoff, P. Knochel*, Chromium(II)-Catalyzed Diastereoselective and Chemoselective Csp2Csp3Cross-Couplings Using Organomagnesium Reagents.J. Am. Chem. Soc.2019,141, 1812718135.

3.S. Han, S. Liu, L. Liu, L. Ackermann,J. Li*, Cobalt-Catalyzed Diastereoselective Difluoroalkyaltion/Giese Addition Domino Reactions.Org. Lett.2019,21, 53875391. (Front Cover)

4.J. Li*, P. Knochel*, Chromium-Catalyzed Cross-Couplings and Related Reactions.Synthesis2019,51, 21002106.

5.J. Li*, E. Tan, N. Keller, Y.-H. Chen, P. M. Zehetmaier, A. C. Jakowetz, T. Bein*, P. Knochel*, Cobalt-Catalyzed Electrophilic Amination with Anthranils: An Expedient Route to Condensed Quinolines.J. Am. Chem. Soc.2019,141, 98103.(highlighted inSynfact2019)

6.M. Tang, Y. Li,S. Han,L. Liu, L. Ackermann,J. Li*, Rhodium(III)-Catalyzed CH Alkylation/Nucleophilic Addition Domino Reaction.Eur. J. Org. Chem.2019, 660664.

7.Y. Da, S. Han, X. Du, S. Liu, L. Liu,J. Li*,Copper(I)-Catalyzed Oxydifluoroalkylation of Alkenes: A Route to Functionalization Lactones.Org. Lett.2018,20. 51495152.

8.J. Li, P. Knochel*, Cobalt-Catalyzed Cross-Couplings between Alkenyl Acetates and Aryl or Alkenyl Zinc Pivalates.Angew. Chem. Int. Ed.2018,57, 1143611440.

9.Liang-Hua Zou*, Cong Zhao, Ping-Gui Li, Ying Wang,J. Li*,Transition-Metal-Free C−S Bond Formation: Synthesis of Polysubstituted Diaryl Sulfides and α‑Thioarylcarbonyl Compounds.J. Org. Chem.2017,82, 12892–12898.

10.X. Zhang*, H. Zheng,J. Li*, F. Xu, J. Zhao, H. Yan*, Selective Catalytic B–H Arylation ofo-Carboranyl Aldehydes by a Transient Directing Strategy.J. Am. Chem. Soc.2017,139, 1451114517.

11.Z. Zhang, S. Han, M. Tang, L. Ackermann*,J. Li*, C–H Alkylations of (Hetero)Arenes by Maleimides and Maleate Ester through Versatile Cobalt(III) Catalysis.Org. Lett.2017,19, 3135–3318.

12.S. Han, W. Ma, Z. Zhang, L. Liu, M. Tang,J. Li*, Mild C(sp3)H Alkylation of 8-Methylquinolines with α,β-Unsaturated Carbonyl Compounds by Rhodium(III) Catalysis.Asain J.Org. Chem.2017,6,1014‒1018.(Front Cover)

13.J. Li*, Z. Zhang, W. Ma, M. Tang, D. Wang, L.-H. Zou, Mild Cobalt(III)-Catalyzed CH Hydroarylation of Conjugated CC/CO Bonds.Adv. Synth. Catal.2017,359,1717–1724.

14.M. Moselage,J. Li(Co-first author), F. Kramm, L. Ackermann*, Ruthenium(II)-Catalyzed Decarbamoylative CC Arylations and Alkylations.Angew. Chem. Int. Ed.2017,55, 5341–5344.

15.Z. Zhang, M. Tang, S. Han, L. Ackermann,J. Li*, Carboxylate Enhanced Rhodium(III)-Catalyzed ArylC–H Alkylation with Conjugated Alkenes under Mild Conditions.J. Org. Chem.2017,82, 664–672.

16.W. Ma*, P. Gandeepan*,J. Li, L. Ackermann*, Recent Advances in Positional-Selective Alkenylations: Removable Guidance for Twofold CH Activation.Org. Chem. Front.2017,4, 14351467.

17.Z. Zhang, M. Tang, L. Zang, L.-H. Zou,J. Li*, Thermolysis of 2-Diazo-3-aryl ketoesters: New Route to α-Aryl Malonates and Aromatic Esters. Tetrahedron Lett.2016,57, 5681–5684.

18.J. Li*, Z. Zhang, M. Tang, X. Zhang, J. Jin,Selective Synthesis of Isoquinolines by Rhodium(III)-Catalyzed C–H/N–H Functionalization with α-Substituted Ketones. Org. Lett.2016,18, 3898–3901.

19.J. Li*, M. Tang, L. Zang, X. Zhang, Z. Zhang, L. Ackermann*,Amidines for Versatile Cobalt(III)-Catalyzed Synthesis of Isoquinolines through C–H Functionalization with Diazo Compounds. Org. Lett.2016,18, 27422745. (highlighted inOrganic Chemistry Portal2017)

20.M. Moselage,J. Li(Co-first author), L. Ackermann*, Cobalt-Catalyzed C–H Activation.ACS Catal.2016,6, 498–525.

21.J. Li, L. Ackermann*, Cobalt(III)-Catalyzed Aryl and Alkenyl CH Aminocarbonylation with Isocyanates and Acyl Azides.Angew. Chem. Int. Ed.2015,54, 8551–8554.

22.J. Li, L. Ackermann*, Cobalt-Catalyzed CH Cyanation of Arenes and Heteroarenes.Angew. Chem. Int. Ed.2015,54, 3635–3638. (Selected ashot paper,highlighted inChemCatChem2015,7, 732).

23.J. Li, L. Ackermann*, Cobalt-Catalyzed CH Arylations with Weakly-Coordinating Amindes and Tetrazoles: Expedient Route to Angiotensin-II-Receptor Blockers.Chem. Eur. J.2015,21, 5718–5722.

24.J. Li, L. Ackermann*, Carboxylate-Assisted Ruthenium(II)-Catalyzed C–H Activations of Monodentate Amides with Conjugated Alkenes.Org. Chem. Front.2015,2, 1035–1039.

25.J. Li, M. John, L. Ackermann*, Amidines for Versatile Ruthenium(II)-Catalyzed Oxidative CH Activations with Internal Alkynes and Acrylates.Chem. Eur. J.2014,20, 5403–5408.

26.J. Li,L. Ackermann*, Ruthenium-Catalyzed Oxidative Alkyne Annulation by CH Activation on Ketimines.Tetrahedron2014,70, 3342–3348.

27.J. Li, H.-M. Hua, Y-B. Tang, S. Zhang, E. Ohkoshi, K.-H Lee, Z. Xiao*, Synthesis and Evaluation of Novel Podophyllotoxin Analogs.Bioorg. Med. Chem. Lett.2012,22, 4293–4295.