吴新鑫

姓名:吴新鑫

职称:副教授


联系方式:xxwu99@suda.edu.cn



2020/01-至今www.优德88.cpm,材料与化学化工学部,副教授

2016/11-2019/12www.优德88.cpm ,材料与化学化工学部,博士后,导师:朱晨教授

2016/07-2016/11扬子江药业集团江苏海岸药业有限公司,高级研究员

2011/09-2016/07华东理工大学,博士,制药工程,导师:叶金星教授

2007/09-2011/07南京工业大学,学士,制药工程

20201月以www.优德88.cpm “优秀青年学者”身份加盟www.优德88.cpm 材化学部有机化学系开展教学科研工作,任副教授、硕士生导师。课题组主要从事自由基化学的方法学研究及其在生物活性分子合成中的应用。在Acc. Chem. Res., Chem. Soc. Rev., Nat. Commun., Angew. Chem. Int. Ed., Chem. Sci.等国际学术刊物上发表学术论文十余篇。主持国家级、省级自然科学基金、中国博士后面上项目以及特别资助等基金多项。曾获得江苏省教育教学与研究成果奖4/5;苏州市自然科学优秀学术论文;国家级大学生创新创业训练计划项目。

教授课程:研究生《理论有机化学》;本科生《有机化学实验》

研究领域自由基化学,不对称催化,绿色化学,药物化学,计算化学

代表性论文:

1. Tingting Feng, Canxiang Liu,Xinxin Wu*, and Chen Zhu*. Redox-neutral manganese-catalyzed synthesis of 1-pyrrolinesChem. Sci.2022,13, 2669–2673.

2. Xinxin Wu, and Chen Zhu*. Combination of radical functional group migration (FGM) and hydrogen atom transfer (HAT).Trends in Chemistry,2022,4, 580-583.

3. Xinxin Wu, Zhigang Ma, Tingting Feng, and Chen Zhu*. Radical-mediated rearrangements: past, present, and future.Chem. Soc. Rev.2021,50, 11577–11613.

4. Xinxin Wu, and Chen Zhu*. Radical Functionalization of Remote C(sp3)–H Bonds Mediated by Unprotected Alcohols and Amides.CCS Chem.2020,2, 813–828.

5. Xinxin Wu, and Chen Zhu*. Radical-Mediated Remote Functional Group Migration.Acc. Chem. Res.2020,53, 1620-1636.

6. Xinxin Wu†, Mingyang Wang†, Leitao Huan, Dongping Wang, Jinwei Wang, and Chen Zhu*. Tertiary-Alcohol-Directed Functionalization of Remote C(sp3)-H Bonds by Sequential Hydrogen Atom and Heteroaryl Migrations.Angew. Chem. Int. Ed.2018,57, 1640-1644. (†co-first author)

7. Xinxin Wu, Hong Zhang, Nana Tang, Zhen Wu, Dongping Wang, Meishan Ji, Yan Xu, Min Wang, Chen Zhu*. Metal-free alcohol-directed regioselective heteroarylation of remote unactivated C(sp3)-H bonds.Nature Communications,2018,9, 3343.

8. Shuo Wu†,Xinxin Wu†, Dongping Wang, and Chen Zhu*. Regioselective Vinylation of Remote Unactivated C(sp3)-H Bonds: Access to Complex Fluoroalkylated Alkenes.Angew. Chem. Int. Ed.2019,58, 1499-1503. (†co-first author)

9. Nana Tang†,Xinxin Wu†, and Chen Zhu*. Practical, Metal-free Remote Heteroarylation of Amides via Unactivated C(sp3)-H Bond Functionalization.Chem. Sci.,2019,10, 6915-6919. (†co-first author)

10. Xinxin Wu, and Chen Zhu*. Radical Functionalization of Remote C(sp3)-H Bonds Mediated by Unprotected Alcohols and Amides.CCS Chem.2020,2, 813-828.

11. Xinxin Wu, and Chen Zhu*. Recent Advances in Alkoxy Radical-promoted C-C and C-H Bond Functionalization Starting from Free Alcohols.Chem. Commun.2019,55, 9747-9756.

12. Xinxin Wu, and Chen Zhu*. Recent Advances in Radical-Mediated C-C Bond Fragmentation of Non-Strained Molecules.Chin. J. Chem.2019,37, 171-182.

13. Xinxin Wu, and Chen Zhu*. Recent Advances in Ring-Opening Functionalization of Cycloalkanols by C-C s-Bond Cleavage.Chem. Rec.2018,18, 587-598.

14. Xinxin Wu, Shuo Wu, and Chen Zhu*. Radical-mediated Difunctionalization of Unactivated Alkenes through Distal Migration of Functional Groups.Tetrahedron Lett.2018,59, 1328-1336.

15. Xinxin Wu, Chunna Meng, Xiaoqian Yuan, Xiaotong Jia, Xuhong Qian, and Jinxing Ye*. Transition-metal-free Visible-light Photoredox Catalysis at Room-temperature for Decarboxylative Fluorination of Aliphatic Carboxylic Acids by Organic Dyes.Chem. Commun.2015,51, 11864-11867.