aKey Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou 215123, China
RSC Adv.,2016,6, 87710-87718
The first utility of neodymium as a mediating-metal in the highly α-regioselective Barbier reaction of diaryl ketones with allyl halides is reported in this paper. This reaction was conveniently carried out under mild conditions in a one-pot fashion with moderate to good yields. The protocol benefited from an availability of starting material, wide substrate scope, and operational simplicity and constituted a powerful alternative approach.
链接：http://pubs.rsc.org/en/content/articlelanding/2016/ra/c6ra18378f/unauth#!divAbstract
