姓名:钟志远 职称:教授、博士生导师 部门:材料学院 联系方式: 课题组网站 |
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学历及学术经历:
研究领域:生物医用高分子材料、药物控制释放、基因释放、生物组织工程、肿瘤靶向治疗。
代表性论文
1.Y.J. Jiang, J. Chen, C. Deng*, E. Suuronen, andZ.Y. Zhong*, Click Hydrogels, Microgels and Nanogels: Emerging Platforms for Drug Delivery and Tissue Engineering,Biomaterials2014, http://dx.doi.org/10.1016/j.biomaterials.2014.03.001.
2.C. Deng, J.T. Wu, R. Cheng, F.H. Meng, H.A. Klok, andZ.Y. Zhong*, Functional Polypeptide and Hybrid Materials: Precision Synthesis via α-Amino Acid N-Carboxyanhydride Polymerization and Emerging Biomedical Applications,Prog. Polym. Sci.2014, 39,330-364.
3.W. Chen, Y. Zou, F.H. Meng, R. Cheng, C. Deng, J. Feijen, andZ.Y. Zhong*, Glyco-Nanoparticles with Sheddable Saccharide Shells: A Unique and Potent Platform for Hepatoma-Targeting Delivery of Anticancer Drugs,Biomacromolecules2014,15, 900-907.
4.Y.N. Zhong, W.J. Yang, H.L. Sun, R. Cheng, F.H. Meng, C. Deng*, andZ.Y. Zhong*, Ligand-Directed Reduction-Sensitive Shell-Sheddable Biodegradable Micelles Actively Deliver Doxorubicin into the Nuclei of Target Cancer Cells,Biomacromolecules2013, 14, 3723-3730.
5.J.R. Zhou, P.P. Chen, C. Deng*, F.H. Meng, R. Cheng, andZ.Y. Zhong*,A Simple and Versatile Synthetic Strategy to Functional Polypeptides via Vinyl Sulfone-Substituted L-Cysteine N-Carboxyanhydride,Macromolecules2013,46, 6723–6730.
6.Y.P. Fan, C. Deng*, R. Cheng, F.H. Meng, andZ.Y. Zhong*, In Situ Forming Hydrogels via Catalyst-Free and Bioorthogonal “Tetrazole–Alkene” Photo-Click Chemistry,Biomacromolecules2013,14, 2814-2821.
7.X.Y. Wang, H.L. Sun, F.H. Meng*, R. Cheng, C. Deng, andZ.Y. Zhong*, Galactose-Decorated Reduction-Sensitive Degradable Chimaeric Polymersomes as a Multifunctional Nanocarrier To Efficiently Chaperone Apoptotic Proteins into Hepatoma Cells,Biomacromolecules2013,14, 2873-2882.
8.Y.D. Gu, Y.N. Zhong, F.H. Meng*, R. Cheng, C. Deng, andZ.Y. Zhong*, Acetal-Linked Paclitaxel Prodrug Micellar Nanoparticles as a Versatile and Potent Platform for Cancer Therapy,Biomacromolecules2013,14, 2772-2780.
9.Y.N. Zhong, W. Wang, L. Cheng,F.H. Meng,Z.Y. Zhong*, and Z. Liu*, Gold Nanorod-Cored Biodegradable Micelles as a Robust and Remotely Controllable Doxorubicin Release System for Potent Inhibition of Drug-Sensitive and -Resistant Cancer Cells,Biomacromolecules2013,14, 2411-2419.
10.L.L. Wu, Y. Zou, C. Deng*, R. Cheng, F.H. Meng, andZ.Y. Zhong*, Intracellular Release of Doxorubicin from Core-Crosslinked Polypeptide Micelles Triggered by Both pH and Reduction Conditions,Biomaterials2013, 34, 5262-5272.
11.W. Chen, M. Zheng, F.H. Meng, R. Cheng, C. Deng, J. Feijen, andZ.Y. Zhong*,In SituForming Reduction-Sensitive Degradable Nanogels for Facile Loading and Triggered Intracellular Release of Proteins,Biomacromolecules2013,14, 1214-1222.
12.H.L. Sun, F.H. Meng*, R. Cheng, C. Deng, andZ.Y. Zhong*, Reduction-Sensitive Degradable Micellar Nanoparticles as Smart and Intuitive Delivery Systems for Cancer Chemotherapy,Expert Opin. Drug Deliv.2013, 10, 1109-1122.
13.R. Cheng, F.H. Meng, C. Deng, H.A. Klok, andZ.Y. Zhong*, Dual and Multi-Stimuli Responsive Polymeric Nanoparticles for Programmed Site-Specific Drug Delivery,Biomaterials2013, 34, 3647-3657.
14.W. Chen, P. Zhong, F.H. Meng*, R. Cheng, C. Deng, J. Feijen, andZ.Y. Zhong*, Redox and pH-Responsive Degradable Micelles for Dually Activated Intracellular Anticancer Drug Release,J. Control. Release2013, 169, 171-179.
15.W. Chen, Y. Zou, J.N. Jia, F.H. Meng, R. Cheng, C. Deng, J. Feijen, andZ.Y. Zhong*, Functional Poly(ε-caprolactone)s via Copolymerization of ε‑Caprolactone and Pyridyl Disulfide-Containing Cyclic Carbonate: Controlled Synthesis and Facile Access to Reduction-Sensitive Biodegradable Graft Copolymer Micelles,Macromolecules2013, 46, 699-707.
16.F.H. Meng, R. Cheng, C. Deng, andZ.Y. Zhong*, Intracellular Drug Release Nanosystems,Materials Today2012, 15, 436-442 (invited review)
17.Y.L. Wu, W. Chen, F.H. Meng, Z.J. Wang, R. Cheng, C. Deng, H.Y. Liu, andZ.Y. Zhong*, Core-Crosslinked pH-Sensitive Degradable Micelles: A Promising Approach to Resolve the Extracellular Stability Versus Intracellular Drug Release Dilemma,J. Control. Release2012, 164, 338-345.
18.C. Deng, Y.J. Jiang, R. Cheng, F.H. Meng, andZ.Y. Zhong*, Biodegradable Polymeric Micelles for Targeted and Controlled Anticancer Drug Delivery: Promises, Progress and Prospects,Nano Today2012, 7, 467-480 (invited review)
19.R.R. Wei, L. Cheng, M. Zheng, R. Cheng, F.H. Meng, C. Deng, andZ.Y. Zhong*, Reduction-Responsive Disassemblable Core-Cross-Linked Micelles Based on Poly(ethylene glycol)-b-poly(N-2-hydroxypropyl methacrylamide)–Lipoic Acid Conjugates for Triggered Intracellular Anticancer Drug Release,Biomacromolecules2012, 13, 2429-2438.
20.Y.F. Du, W. Chen, M. Zheng, F.H. Meng, andZ.Y. Zhong*, pH-Sensitive Degradable Chimaeric Polymersomes for the Intracellular Release of Doxorubicin Hydrochloride,Biomaterials2012, 33, 7291-7299.
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