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倪沛红
姓名：倪沛红
职称：教授、博士生导师

部门：材料学院
联系方式：
Professor in Macromolecular Science

College of Chemistry, Chemical Engineering and Materials Science

Soochow University

Suzhou，Jiangsu，215123，China

Tel: 86-512-65882047
E-mail: phni@suda.edu.cn


课题组网站

学历及学术经历:

1982年毕业于南京大学化学系高分子化学专业，1988年获www.优德88.cpm 有机化学专业硕士学位，留校在化学系任教。1997.9-2000.12，复旦大学高分子科学系攻读博士学位。其间，1998.9-1999.10，美国东密歇根大学访问学者。2000年获复旦大学高分子化学与物理专业博士学位。2003年被聘为www.优德88.cpm 教授、高分子化学与物理专业博士生导师。主持完成国家自然科学基金面上项目4项，省部级项目5项。在Macromolecules、ACS Applied Materials & Interfaces、Journal of Materials Chemistry B、Polymer Chemistry、Soft Matter、Langmuir、J. Polym. Sci. Part A: Polym. Chem.等刊物发表研究论文110多篇，撰写英文著作3章，获授权的中国发明专利25项。

研究领域:

(1)设计合成环境响应性生物医用高分子材料；(2)氟碳－碳氢杂化的两亲性聚合物及其应用; (3)乳液及细乳液聚合；(4)天然高分子的改性。


代表性论文：

  1. Youwen Cao, Jinlin He, Jie Liu, Mingzu Zhang,Peihong Ni*, “Folate-conjugated polyphosphoester with reversible cross-linkage and reduction sensitivity for drug delivery”,ACS Applied Materials & Interfaces,2018,10(9),7811-7820.

  2. Xueqiong Du, Yue Sun, Mingzu Zhang, Jinlin He andPeihong Ni*, “Polyphosphoester-camptothecin prodrug with reduction-response preparedviamichael addition polymerization and click reaction”,ACS Applied Materials & Interfaces,2017,9, 13939-13949.

  3. Yue Sun, Xueqiong Du, Jinlin He, Jian Hu, Mingzu Zhang andPeihong Ni*, “Dual-responsive core-crosslinked polyphosphoester-based nanoparticles for pH/redox-triggered anticancer drug delivery”,Journal of Materials ChemistryB,2017,5, 3771-3782.

  4. Zixu Gu, Jun Cheng, Mingzu Zhang, Jinlin He,Peihong Ni*, “Effect of Sequence structure on wetting behaviors of fluorinated methacrylate polymers based on perfluorohexylethyl methacrylate and stearyl acrylate”,Chinese Journal of Polymer Science,2017,35(9), 1061-1072.

  5. Zixu Gu, Jun Cheng, Mingzu Zhang, Jinlin He,Peihong Ni*, “Effect of groups atα-position and side-chain structure of comonomers on surface energy and surface reorganization of fluorinated methacrylate copolymer”,Polymer,2017,114, 79-87.

  6. Dongling Caoa, Jinlin Hea, Jiaying Xub, Mingzu Zhanga, Lin Zhaob, Guangxin Duanb, Youwen Caoa, RuhongZhoub,c,d,* andPeihong Nia,*, “Polymeric prodrugs conjugated with reduction-sensitive dextran-camptothecin and pH-responsive dextran-doxorubicin: An effective combinatorial drug delivery platform for cancer therapy”,Polymer Chemistry,2016,7, 4198-4212.

  7. Sen Li, Jinlin He*, Mingzu Zhang, Hairong Wang,Peihong Ni*, “Multicompartment morphologies self-assembled from fluorinated ABC triblock terpolymers: Effects of flexible and rigid hydrophobic moieties”,Polymer Chemistry,2016,7, 1773-1781.

  8. Kai Ren, Mingzu Zhang, Jinlin He, Yixian Wu,Peihong Ni*, “Polymeric prodrug paclitaxel-poly(lactic acid)-b-polyisobutylene and its application in coatings of drug eluting stent”,ACS Applied Materials & Interfaces,2015,7(21), 11263–11271.

  9. Qingqing Zhang, Jinlin He*, Mingzu Zhang,Peihong Ni*, “Polyphosphoester-conjugated camptothecin prodrug with disulfide linkage for potent reduction-triggered drug delivery”,Journal of Materials Chemistry B,2015,3, 4922-4932.

  10. Hairong Wang, Jinlin He, Mingzu Zhang, Kam Chiu Tam*,Peihong Ni*, “A new pathway towards polymer modified cellulose nanocrystalsviaa “grafting onto” process for drug delivery”,Polymer Chemistry,2015,6, 4206-4209..

  11. Jian Hu, Jinlin He, Dongling Cao, Mingzu Zhang,Peihong Ni*, “Core cross-linked polyphosphoester micelles with folate-targeted and acid-cleavable features for pH-triggered drug delivery”,Polymer Chemistry,2015,6, 3205 -3216. (Front cover article)

  12. Jian Hu, Jinlin He*, Mingzu Zhang,Peihong Ni*, “Precise modular synthesis and a structure–property study of acid-cleavable star-block copolymers for pH-triggered drug delivery”,Polymer Chemistry,2015,6, 1553-1566.

  13. 胡健，何金林，张明祖，倪沛红*. “聚磷酸酯的合成及在生物医用材料中的应用”,《高分子通报》,2015,10, 51-65.

  14. Jiao Bian, Ying Hao, Jinlin He*, Wenling Zhang, Mingzu Zhang,Peihong Ni*, “Synthesis and characterization of a biodegradable ABC triblock terpolymer for co-delivery carrier of doxorubicin and DNA”,Journal of Polymer Science,Part A:Polymer Chemistry,2014,52, 3005–3016.

  15. Yang Zhang, Jinlin He*, Dongling Cao, Mingzu Zhang,Peihong Ni*, “Galactosylated reduction and pH dual-responsive triblock terpolymer Gal-PEEP-a-PCL-ss-PDMAEMA : a Multifunctional carrier for the targeted and simultaneous delivery of doxorubicin and DNA”,Polymer Chemistry,2014,5, 5124-5138.

  16. Ying Hao, Jinlin He, Sen Li, Jian Liu, Mingzu Zhang,Peihong Ni*, “Synthesis of an acid-cleavable and fluorescent amphiphilic block copolymer as a combined delivery vector of DNA and doxorubicin”,Journal of Materials Chemistry B,2014,2, 4237-4249.

  17. Yunfeng Tao, Jinlin He, Mingzu Zhang, Jian Liu,Peihong Ni*, “Galactosylated biodegradablepoly(e-caprolactone-co-phosphoester) random copolymer nanoparticles for potent hepatoma-targeting delivery of doxorubicin”,Polymer Chemistry,2014,5, 3443-3452.

  18. 肖燕，何金林，陶云锋，张明祖，胡健，倪沛红*.“基于功能化聚磷酸酯嵌段共聚物的微凝胶和水凝胶的制备与表征”,《高分子学报》,2014,1, 122-130.

  19. 李森，张明祖，何金林，倪沛红*.“含氟聚甲基丙烯酸酯/聚异丁烯嵌段共聚物的成膜性质研究”,《高分子学报》,2014,12, 1648-1658.

  20. 郝莹，张洋，何金林，尚修娟，张明祖，倪沛红*. “半乳糖胺修饰阳离子型刷形嵌段共聚物的合成与表征”,《化学学报》,2014,72, 569-576.

  21. Hairong Wang, Jinlin He, Mingzu Zhang, Yunfeng Tao, Fei Li, Kam C. Tam,Peihong Ni*,“Biocompatible and acid-cleavable poly(ε-caprolactone)-acetal-poly(ethylene glycol)-acetal-poly(ε-caprolactone) triblockcopolymers: Synthesis, characterization and pH-triggered doxorubicin delivery”,Journal of Materials Chemistry B,2013,1, 6596-6607. (Front inside cover article)

  22. Guoyi Zhang, Mingzu Zhang, Jinlin He,Peihong Ni*, “Synthesis and characterization of a new multifunctional polymeric prodrug paclitaxel-polyphosphoester-folic acid for targeted drug delivery”,Polymer Chemistry,2013,4, 4515-4525.

  23. Ying Hao, Jinlin He, Mingzu Zhang, Yunfeng Tao, Jian Liu,Peihong Ni*, “Synthesis and characterization of novel brush copolymers with biodegradable polyphosphoester side chains for gene delivery”,Journal of Polymer Science,Part A:Polymer Chemistry,2013,51, 2150-2160. (Spotlight on Polymer Chemistry Issue 10,http://www.materialsviews.com/spotlight-on-polymer-chemistry-volume-51-issue-10/)

  24. Jiao Bian, Mingzu Zhang, Jinlin He,Peihong Ni*, “Preparation and self-Assembly of double hydrophilic poly(ethylethylene phosphate)-block-poly[2-(succinyloxy)ethyl methacrylate] diblock copolymers for drug delivery”,Reactive & Functional Polymers,2013,73, 579-587.

  25. Huaichao Wang, Mingzu Zhang,Peihong Ni*, Jinlin He, Ying Hao, Yixian Wu, “Synthesis of pH-responsive amphiphilic diblock copolymers containing polyisobutylene via oxyanion-initiated polymerization and their multiple self-assembly morphologies”,Chinese Journal of Polymer Science,2013,31 (2), 218-231. (Cover article)

  26. 胡健,‡何金林,‡张明祖,倪沛红*. “点击化学在拓扑结构聚合物合成中的应用”,《高分子学报》,2013,3, 300-319. (‡共同第一作者)

  27. Jinlin He, Mingzu Zhang,Peihong Ni*, “Rapidlyin situforming polyphosphoester-based hydrogels for injectable drug delivery carriers”.Soft Matter,2012,8, 6033-6038.

  28. Ying Hao, Mingzu Zhang, Jinlin He,Peihong Ni*, “Magnetic DNA vector constructed from PDMAEMA polycation and PEGylated brush-type polyanion with crosslinkable shell”,Langmuir,2012,28, 6448-6460.

  29. Haiyan Shao, Mingzu Zhang, Jinlin He,Peihong Ni*, “Synthesis and characterization of amphiphilic poly(e-caprolactone)-b-polyphosphoester diblock copolymers bearing multifunctional pendant groups”,Polymer,2012,53, 2854-2863.

  30. Shihua Zhang, Zixu Gu, Ying Hao, Mingzu Zhang,Peihong Ni*, “Synthesis of double-hydrophilic block copolymers via combination of oxyanion-initiated polymerization and polymer reaction for fabricating magnetic target gene carrier”,Journal of Polymer Science,Part A:Polymer Chemistry,2011,49, 4081-4091.

  31. 张世华，朱慧文，张明祖，倪沛红*.“原子转移自由基聚合与“Click”反应相结合制备Fe3O4@SiO2-g-PDMAEMA及其性质研究”,《化学学报》,2011,69,2166-2172.

  32. Xu Liu,Peihong Ni*, Jinlin He, Mingzu Zhang, “Synthesis and micellization of pH/temperature-responsive double-hydrophilic diblock copolymers polyphosphoester-block-poly[2-(dimethylamino)ethyl methacrylate] prepared via ROP and ATRP”,Macromolecules,2010,43, 4771-4781.

  33. Yaojuan Wu,Peihong Ni*, Mingzu Zhang, Xiulin Zhu*, “Fabrication of microgels via supramolecular assembly of cyclodextrin-containing star polycations and oppositely charged linear polyanions”,Soft Matter,2010,6, 3751-3758.

  34. Jinlin He,Peihong Ni,* Sai Wang, Haiyan Shao, Mingzu Zhang, Xiulin Zhu*, “Synthesis and physicochemical characterization of biodegradable and pH-responsive hydrogels based on polyphosphoester for protein delivery”,Journal of Polymer Science,Part A:Polymer Chemistry,2010,48, 1919-1930.

  35. Wenling Zhang, Jinlin He, Zhuang Liu,Peihong Ni,* Xiulin Zhu*, “Biocompatible and pH-responsive triblock copolymer mPEG-b-PCL-b-PDMAEMA: Synthesis, self-assembly and application”,Journal of Polymer Science,Part A:Polymer Chemistry,2010,48, 1079-1091.

  36. Mingzu Zhang, Jinlin He, Jiang Mao, Cuicui Liu, Hairong Wang, Yinfeng Huang,Peihong Ni*, “Kinetics of styrene miniemulsion polymerization using poly[(stearyl methacrylate-co-(N,N-dimethylamino)ethyl methacrylate] as surfactant”,Colloids and Surfaces A: Physicochem. Eng. Aspects,2010,360, 190-197.

  37. Ying Hao, Mingzu Zhang, Jie Xu, Cuicui Liu,Peihong Ni*, “Synthesis and micellization of triblock copolymers containing MePEG-b-PDMAEMA and fluoropolymer: Effect of block lengths on self-assembly”,Journal of Macromolecular Science A-Pure and Applied Chemistry,2010,47, 941-951.

  38. 袁媛，张明祖，张虎，倪沛红*.“pH响应性含氟三嵌段共聚物的制备及性质研究”,《化学学报》,2010,68(15), 1537-1544.

  39. Zixu Gu, Yuan Yuan, Jinlin He, Mingzu Zhang,Peihong Ni*, “Facile approach for DNA encapsulation in functional polyion complex for triggered intracellular gene delivery: Design, synthesis, and mechanism”,Langmuir,2009,25, 5199-5208.

  40. Guixiang Sun, Mingzu Zhang, Jinlin He,Peihong Ni*, “Synthesis of amphiphilic cationic copolymers poly[2-(methacryloyloxy)ethyl trimethylammonium chloride-co-stearyl methacrylate] and their self-assembly behavior in water and water-ethanol mixtures”,Journal of Polymer Science,Part A:Polymer Chemistry,2009,47, 4670-4684.

  41. Cuicui Liu, Jinlin He, Qun Zhao, Mingzu Zhang,Peihong Ni*, “Well-defined poly[(dimethylamimo)ethyl methacrylate]-b-poly(fluoroalkyl methacrylate) diblock copolymers: Effects of different fluoroalkyl groups on the solution properties”,Journal of Polymer Science,Part A:Polymer Chemistry,2009,47, 2702-2712.

  42. Cuicui Liu,Peihong Ni*, Xiao Fang, Xiaodong Zhou, “Synthesis of amphiphilic diblock copolymers poly[2-(N,N-dimethylamino)ethyl methacrylate]-b-poly(stearyl methacrylate) and their self-assembly in mixed solvent”,Colloid & Polymer Science,2009,287, 45-55.

  43. Hu Zhang,Peihong Ni*, Jinlin He, Cuicui Liu, “Novel fluoroalkyl end-capped amphiphilic diblock copolymers with pH/temperature response and self-assembly behavior”,Langmuir,2008,24, 4647-4654.

  44. Jinlin He,Peihong Ni*, Cuicui Liu, “Synthesis and characterization of amphiphilic fluorinated pentablock copolymers based on Pluronic F127”,Journal of Polymer Science,Part A:Polymer Chemistry,2008,46, 3029-3041.

Book Chapters:

  1. Peihong Ni,Shoukuan Fu, “Chapter3: Preparation of Microlatexes Using Polymeric Surfactants or Mixed Surfactants”, inColloid Polymers: Synthesis and Characterization,Edited by Abdelhamid Elaïssari,Surfactant Science Series (Volume115). Published by Marcel Dekker, Inc., New York, p47-76, 2003.

  2. Peihong Ni,“Chapter2: Nanoparticles Comprising pH/Temperature-Responsive Amphiphilic Block Copolymers and Their Applications in Biotechnology”, inColloidal Nanoparticles in Biotechnology,Edited by Abdelhamid Elaïssari, Copyright Ó 2008 John Wiley & Sons, Inc. p31-63, 2008.

  3. Peihong Ni*, Xiulin Zhu, Xiaodong Zhou, “Chapter19: Kinetics and colloidal stability of RAFT/miniemulsion polymerization of MMA using comblike polymeric surfactants”, inControlled/Living Radical Polymerization: Progress in RAFT, DT, NMP & OMRP; Edited by Krzysztof Matyjaszewski; ACS Symposium Series 1024; Copyright Ó 2009 American Chemical Society, Oxford University Press, p293-302,2009.