李杰
姓名:李杰
职称:教授


联系方式:jjackli@suda.edu.cn

个人主页:https://www.x-mol.com/groups/JieLi



2020.01至今www.优德88.cpm ,材料与化学化工学部,教授

2017.102019.11慕尼黑大学,化学院,Research Associate(合作导师:Prof. Paul Knochel

2015.102017.09江南大学,药学院,特聘研究员

2011.102015.07哥廷根大学,有机化学(导师:Prof. Lutz Ackermann;博士论文获summa cum laude

2008.092011.10沈阳药科大学&中国医学科学院药物研究所,药物化学(导师:华会明教授&肖志艳研究员)

2004.092008.06天津商业大学,制药工程

研究领域及经历围绕新试剂、新反应的发展,积极开展基于试剂导向的合成有机化学研究。迄今,在包括Nat. Commun.1篇)、J.Am. Chem. Soc.3Angew. Chem., Int. Ed.6)等期刊发表研究论文三十余篇。获得2021年度Thieme Chemistry Journals Awardees入选2016年度江苏省双创博士2015年博士论文荣获summa cum laude”–优博应邀在国际、国内科研院校做学术报告十余次。

代表性研究论文:

1. J. Wang, Z. Duan, X. Liu, S. Dong, K. Chen,J. Li*,Salt-Stabilized Silylzinc Pivalates for Nickel-Catalyzed Carbosilylation of Alkenes,Angew. Chem.,Int. Ed.,2022,61, e202202379.

2. Y. Hu, X. Liu, Z. Ren, B. Hu,J. Li*,Csp3H Monofluoroalkenylation via Stereoselective CF Bond Cleavage,Chem.Commun.,2022,58, 2734-2737.

3. Y. Hu, B. Hu, X. Liu, Z. Ren,J. Li*,Recent Developments in Catalytic Cross-Couplings with Unsaturated Carboxylates,Org. Biomol. Chem.,2021,19, 7754-7767.

4.X. Cheng, X. Liu, S. Wang, Y. Hu, B. Hu, A. Lei*,J. Li*,Organozinc Pivalates for Cobalt-Catalyzed Difluoroalkylarylation of Alkenes,Nat. Commun.,2021,12,43664375.

5.B. Hu, X. Cheng, Y. Hu, X. Liu, K.Karaghiosoff,J. Li*,Rhenium-Catalyzed ArylAcylcyclization between Enol Lactones and Organomagnesium Halides: Facile Synthesis of Indenones,Angew. Chem., Int. Ed.,2021,60, 1549715502.

6.X. Cheng, X. Liu, S. Wang, Y. Hu, B. Hu, A. Lei*,J. Li*,Organozinc Pivalates for Cobalt-Catalyzed Difluoroalkylarylation of Alkenes and Mechanistic Insights,nature portfolio,2021, DOI:10.21203/rs.3.rs-156355/v1.

7.Z. Zhang, H. Chen, N. Keller, Q. Xiong, L. Liu, Y. Lan*, T. Bein*,J. Li*,Dehydrogenative6π Heterocyclization under Visible Light IrradiationandMechanistic Insights.Org. Chem. Front.,2021,8,37883795.

8.L. Liu,Mingran Si,Shengnan Han, Y. Zhang,J. Li*,Copper-Catalyzed Regioselective Sulfonylcyanation of Vinylarenes.Org. Chem. Front.,2020,7,20292034.

9.L. Liu, Z. Zhang, Y. Wang, Y. Zhang,J. Li*,Electrophilic Amination with Anthranils through Cobalt(III)-Catalyzed C(sp3)H Activation.Synthesis2020,52, 38813890.

10.J. Li*,Q. Ren,X.Cheng, K.Karaghiosoff,P. Knochel*, Chromium(II)-Catalyzed Diastereoselective and Chemoselective Csp2Csp3Cross-Couplings Using Organomagnesium Reagents.J.Am.Chem.Soc.,2019,141, 1812718135.

11. S. Han, S. Liu, L. Liu, L. Ackermann,J. Li*,Cobalt-Catalyzed Diastereoselective Difluoroalkyaltion/Giese Addition Domino Reactions.Org. Lett.,2019,21, 53875391.

12.J. Li*,P.Knochel*,Chromium-Catalyzed Cross-Couplings and Related Reactions.Synthesis2019,51, 21002106.

13.J. Li*,E. Tan, N. Keller, Y.-H. Chen, P. M. Zehetmaier, A. C. Jakowetz, T. Bein*,P. Knochel*, Cobalt-CatalyzedElectrophilic Amination with Anthranils: An Expedient Route to Condensed Quinolines.J.Am.Chem.Soc.,2019,141, 98103.

14. M. Tang, Y. Li,S. Han,L. Liu, L. Ackermann,J. Li*,Rhodium(III)-Catalyzed CH Alkylation/Nucleophilic Addition Domino Reaction.Eur. J. Org. Chem.,2019, 660664.

15. Y.Da, S.Han, X.Du, S.Liu, L.Liu,J. Li*,Copper(I)-Catalyzed Oxydifluoroalkylation of Alkenes: A Route to Functionalization Lactones.Org. Lett.,2018,20.51495152.

16.J. Li, P. Knochel*, Cobalt-Catalyzed Cross-Couplings between Alkenyl Acetates and Aryl or AlkenylZinc Pivalates.Angew. Chem., Int. Ed.,2018,57, 1143611440.

17. Liang-Hua Zou*, Cong Zhao, Ping-Gui Li, Ying Wang,J. Li*,Transition-Metal-Free C−S Bond Formation: Synthesis of Polysubstituted Diaryl Sulfides and αThioarylcarbonyl Compounds.J. Org. Chem.,2017,82, 12892–12898.

18. X. Zhang*, H. Zheng,J. Li*, F. Xu, J. Zhao, H. Yan*, Selective Catalytic B–H Arylation ofo-Carboranyl Aldehydes by a Transient Directing Strategy.J. Am. Chem. Soc.,2017,139, 1451114517.

19. Z. Zhang, S. Han, M. Tang, L. Ackermann*,J. Li*, C–H Alkylations of (Hetero)Arenes by Maleimides and Maleate Ester through Versatile Cobalt(III) Catalysis.Org. Lett.,2017,19, 3315–3318.

20. S. Han, W. Ma, Z. Zhang, L. Liu, M. Tang,J. Li*, Mild C(sp3)H Alkylation of 8-Methylquinolines with α,β-Unsaturated Carbonyl Compounds by Rhodium(III) Catalysis.Asain J.Org. Chem.,2017,6,10141018.

21.J. Li*, Z. Zhang, W. Ma, M. Tang, D. Wang, L.-H. Zou, Mild Cobalt(III)-Catalyzed CH Hydroarylation of Conjugated CC/CO Bonds.Adv. Synth. Catal.,2017,359,1717–1724.

22. M. Moselage,J. Li(Co-first author), F. Kramm, L. Ackermann*, Ruthenium(II)-Catalyzed Decarbamoylative CC Arylations and Alkylations.Angew. Chem., Int. Ed.,2017,55, 5341–5344.

23. Z. Zhang, M. Tang, S. Han, L. Ackermann,J. Li*, Carboxylate Enhanced Rhodium(III)-Catalyzed ArylC–H Alkylation with Conjugated Alkenes under Mild Conditions.J. Org. Chem.,2017,82, 664–672.

24. W. Ma*, P. Gandeepan*,J. Li, L. Ackermann*, Recent Advances in Positional-Selective Alkenylations: Removable Guidance for Twofold CH Activation.Org. Chem. Front.,2017,4, 14351467.

25. Z. Zhang, M. Tang, L. Zang, L.-H. Zou,J. Li*, Thermolysis of 2-Diazo-3-aryl ketoesters: New Route to α-Aryl Malonates and Aromatic Esters. Tetrahedron Lett.,2016,57, 5681–5684.

26.J. Li*, Z. Zhang, M. Tang, X. Zhang, J. Jin,Selective Synthesis of Isoquinolines by Rhodium(III)-Catalyzed C–H/N–H Functionalization with α-Substituted Ketones.Org. Lett.,2016,18, 3898–3901.

27.J. Li*, M. Tang, L. Zang, X. Zhang, Z. Zhang, L. Ackermann*,Amidines for Versatile Cobalt(III)-Catalyzed Synthesis of Isoquinolines through C–H Functionalization with Diazo Compounds.Org. Lett.,2016,18, 27422745.

28. M. Moselage,J. Li(Co-first author), L. Ackermann*, Cobalt-Catalyzed C–H Activation.ACS Catal.,2016,6, 498–525.

29.J. Li, L. Ackermann*, Cobalt-Catalyzed CH Cyanation of Arenes and Heteroarenes.Angew. Chem., Int. Ed.,2015,54, 3635–3638.

30.J. Li, L. Ackermann*, Cobalt(III)-Catalyzed Aryl and Alkenyl CH Aminocarbonylation with Isocyanates and Acyl Azides.Angew. Chem., Int. Ed.,2015,54, 8551–8554.

31.J. Li, L. Ackermann*, Cobalt-Catalyzed CH Arylations with Weakly-Coordinating Amindes and Tetrazoles: Expedient Route to Angiotensin-II-Receptor Blockers.Chem. Eur. J.,2015,21, 5718–5722.

32.J. Li, L. Ackermann*, Carboxylate-Assisted Ruthenium(II)-Catalyzed C–H Activations of Monodentate Amides with Conjugated Alkenes.Org. Chem. Front.,2015,2, 1035–1039.

33.J. Li, M. John, L. Ackermann*, Amidines for Versatile Ruthenium(II)-Catalyzed Oxidative CH Activations with Internal Alkynes and Acrylates.Chem. Eur. J.,2014,20, 5403–5408.

34.J. Li,L. Ackermann*, Ruthenium-Catalyzed Oxidative Alkyne Annulation by CH Activation on Ketimines.Tetrahedron2014,70, 3342–3348.

35.J. Li, H.-M. Hua, Y-B. Tang, S. Zhang, E. Ohkoshi, K.-H Lee, Z. Xiao*, Synthesis and Evaluation of Novel Podophyllotoxin Analogs.Bioorg. Med. Chem. Lett.,2012,22, 4293–4295.