课题组网站：http://macbio.suda.edu.cn/

学历及学术经历:

2007年本科毕业于武汉理工大学高分子材料与工程专业，随后在本校保送直博，2012年7月获得武汉理工大学生物材料学博士学位（博士生导师：陈红教授）。2012年8月加入www.优德88.cpm 材料与化学化工学部高分子科学与工程系，并于2015年7月晋升为副教授。2019.09-2020.09新加坡国立大学访问学者。先后担任国际期刊Polymer Chemistry和Colloids and Surfaces B: Biointerfaces编辑助理。

研究领域:生物材料表面改性及功能化；蛋白质、细胞与材料表面的相互作用研究；多功能血液接触材料表面的构建；高分子材料表面的类肝素化研究；微流控芯片材料表面改性及生物功能化

主要荣誉：

2019年指导江苏省大学生创新创业训练计划项目

2020年江苏省科技副总

2021年江苏省“青蓝工程”优秀青年骨干教师培养对象

2021年www.优德88.cpm 本科毕业设计（论文）优秀指导教师

2021年江苏省本科优秀毕业论文（设计）一等奖指导教师

2022年第二届www.优德88.cpm 教师教学创新大赛一等奖

近年主持的科研项目：

(1)国家自然科学基金面上项目，2021.01-2024.12，项目负责人。

(2)材料表面改性技术的开发（横向项目），2020.7-2023.7，项目负责人。

(3)国家自然科学基金面上项目，2018.01-2021.12，项目负责人。

(4)国家自然科学基金青年科学基金项目，2014.01-2016.12，项目负责人。

(5)江苏省高校自然www.优德88.cpm 面上项目，2013.08-2015.12，项目负责人。

(6)中国博士后科学基金面上资助，2013.09-2016.12，项目负责人。

代表性论文：

[1] X. Liang, A. Zhang, W. Sun, J. Lei,X. Liu*, Z. Tang and H. Chen, Vascular cell behavior on glycocalyx–mimetic surfaces: simultaneous mimicking of the chemical composition and topographical structure of the vascular endothelial glycocalyx, Colloids and Surfaces B: Biointerfaces, 212 (2022) 112337.

[2] Y. Li, W. Sun, A. Zhang, S. Jin, X. Liang, Z. Tang,X. Liu*and H. Chen, Vascular cell behavior on heparin-like polymers modified silicone surfaces: The prominent role of the lotus leaf-like topography, Journal of Colloid and Interface Science, 603 (2021) 501-510.

[3] A. Zhang, W. Sun, X. Liang, X. Chen, Y. Li,X. Liu*and H. Chen*, The role of carboxylic groups in heparin-mimicking polymer-functionalized surfaces for blood compatibility: enhanced vascular cell selectivity, Colloids and Surfaces B: Biointerfaces, 201 (2021) 111653.

[4] W. Sun, Wei, S. Jin, A. Zhang, J. Huang, Y. Li,X. Liu*,and H. Chen*, Vascular cell responses to silicone surfaces grafted with heparin-like polymers: surface chemical composition vs. topographic patterning, Journal of Materials Chemistry B, 8 (2020) 9151-9161.

[5] S. Jin, J. Huang, X. Chen, H. Gu, D. Li*, A. Zhang,X. Liu*, H. Chen, Nitric oxide-generating antiplatelet polyurethane surfaces with multiple additional biofunctions via cyclodextrin-based host–guest interactions, ACS Applied Bio Materials, 3 (2020) 570-576.

[6] X. Chen, H. Gu, Z. Lyu,X. Liu*, L. Wang*, H. Chen, J.L. Brash, Sulfonate groups and saccharides as essential structural elements in heparin-mimicking polymers used as surface modifiers: optimization of relative contents for antithrombogenic properties, ACS Applied Materials & Interfaces, 10 (2018) 1440-1449.

[7] S. Li, B. Liu, T. Wei, C. Hu, Y. Hang, Y. Dong,X. Liu*, H. Chen*, Microfluidic channels with renewable and switchable biological functionalities based on host–guest interactions, Journal of Materials Chemistry B, 6 (2018) 8055-8063.

[8] S. Jin, H. Gu, X. Chen,X. Liu*, W. Zhan, T. Wei, X. Sun*, C. Ren, H. Chen, A facile method to prepare a versatile surface coating with fibrinolytic activity, vascular cell selectivity and antibacterial properties, Colloids and Surfaces B: Biointerfaces, 167 (2018) 28-35.

[9] J. Wu, C. Hu, Z. Tang, Q. Yu,X. Liu*, H. Chen, Tissue-engineered vascular grafts: balance of the four major requirements, Colloid and Interface Science Communications, 23 (2018) 34-44.

[10] H. Gu, X. Chen,X. Liu*, W. Zhan, Z. Lyu, Q. Yu, Z. Wu*, H. Chen, A hemocompatible polyurethane surface having dual fibrinolytic and nitric oxide generating functions, Journal of Materials Chemistry B, 5 (2017) 980-987.

[11] M. Wang,X. Liu*, Z. Lyu, H. Gu, D. Li, H. Chen, Glycosaminoglycans (GAGs) and GAG mimetics regulate the behavior of stem cell differentiation, Colloids and Surfaces B: Biointerfaces, 150 (2017) 175-182.

[12] H. Gu, X. Chen, Q. Yu,X. Liu*, W. Zhan, H. Chen*, J.L. Brash, A multifunctional surface for blood contact with fibrinolytic activity, ability to promote endothelial cell adhesion and inhibit smooth muscle cell adhesion, Journal of Materials Chemistry B, 5 (2017) 604-611.

[13] J. Du,X. Liu*, W. Liu, Z. Wu*, H. Chen, One-step preparation of vinyl-functionalized material surfaces: a versatile platform for surface modification, Science China Chemistry, 57 (2014) 654-660.

[14] X. Liu, L. Yuan, D. Li, Z. Tang, Y. Wang, G. Chen, H. Chen*, J.L. Brash*, Blood compatible materials: state of the art, Journal of Materials Chemistry B, 2 (2014) 5718-5738.

[15] Y. Wang, F. Zhou,X. Liu*, L. Yuan, D. Li, Y. Wang, H. Chen*, Aptamer-modified micro/nanostructured surfaces: efficient capture of Ramos cells in serum environment, ACS Applied Materials & Interfaces, 5 (2013) 3816-3823.

[16] X. Liu, W. Tong, Z. Wu*, W. Jiang, Poly(N-vinylpyrrolidone)-grafted poly(dimethylsiloxane) surfaces with tunable microtopography and anti-biofouling properties, RSC Advances, 3 (2013) 4716-4722.

[17] X. Liu, Y. Xu, Z. Wu*, H. Chen*, Poly(N-vinylpyrrolidone)-modified surfaces for biomedical applications, Macromolecular Bioscience, 13 (2013) 147-154.

[18] X. Liu, K. Sun, Z. Wu*, J. Lu, B. Song, W. Tong, X. Shi, H. Chen*, Facile synthesis of thermally stable poly(N-vinylpyrrolidone)-modified gold surfaces by surface-initiated atom transfer radical polymerization, Langmuir, 28 (2012) 9451-9459.

[19] X. Liu, Z. Wu*, D. Li, H. Chen, Poly(N-vinylpyrrolidone)-modified surfaces repel plasma protein adsorption, Chinese Journal of Polymer Science, 30 (2012) 235-241.

[20] X. Liu, Z. Wu*, F. Zhou, D. Li, H. Chen*, Poly(vinylpyrrolidone-b-styrene) block copolymers tethered surfaces for protein adsorption and cell adhesion regulation, Colloids and Surfaces B: Biointerfaces, 79 (2010) 452-459.