于谦
姓名:于谦
职称:教授、博士生导师

联系方式:

Tel: +86-512-65880583

Email: yuqian@suda.edu.cn


学历及学术经历:

20056月获武汉理工大学化学工程学院工学学士学位,20116月获武汉理工大学材料科学与工程学院工学博士学位。20118月至20148月在美国Duke大学生物医学工程系从事博士后研究工作。20148月加入www.优德88.cpm 材料与化学化工学部任特聘副教授,20187月破格晋升为教授。

以第一/通讯作者在生物表界面和功能材料领域内国内外重要期刊如Advanced Functional Materials, Bioactive Materials, Advanced Healthcare Materials, ACS Applied Materials Interfaces等发表综述和研究论文70余篇(2ESI热点论文和7ESI高被引论文,另有多篇论文选为期刊封面),论文总引用次数超过5500次,H因子为42。主持国家自然科学基金面上项目、江苏省自然科学基金优秀青年基金项目、江苏省高等学校自然www.优德88.cpm 重大项目等多项科研项目。

入选2018年江苏省优秀青年基金计划,2015年度苏州市高等院校、科研院所紧缺高层次人才引进资助计划。目前担任胶体与表界面领域国际期刊Colloids and Interface Science Communications (Elsevier出版社)主编,同时担任国际期刊Colloids and interfaces B: Biointerfaces, JCIS Open (Elsevier出版社)Smart Materials in Medicine (KeAi出版社)编委,中国生物材料学会生物材料表界面工程分会常务委员。

研究领域:

生物材料的表面改性与功能化;新型抗菌抗生物被膜表面的设计与应用;刺激响应性材料在生物医用及生物检测领域的应用

代表性论文(截止20238月)

邀请综述

(1) D. Jia, Y. Lin, Y. Zou, Y. Zhang*,Q. Yu*, Recent advances in dualfunction superhydrophobic antibacterial surfaces,Macromol. Biosci., 2023, 23, 2300191.

(2) Y. Qu, K. Lu, Y. Zheng, C. Huang, G. Wang*, Y. Zhang*,Q. Yu*, Photothermal scaffolds/surfaces for regulation of cell behaviors,Bioact. Mater., 2022, 8, 449-477.(ESI高被引论文)

(3) T. Wei, Y. Qu, Y. Zou, Y. Zhang*,Q. Yu*, Exploration of smart antibacterial coatings for practical applications,Curr. Opin. Chem. Eng., 2021, 34, 100727.

(4) Y. Zou, Y. Zhang*,Q. Yu*, H. Chen, Dual-function antibacterial surfaces to resist and kill bacteria: Painting a picture with two brushes simultaneously,J. Mater. Sci. Technol., 2021, 70, 24-38.(ESI高被引论文、封面论文)

(5) Y. Zou, Y. Zhang*,Q. Yu*, H. Chen, Photothermal bactericidal surfaces: killing bacteria using light instead of biocides,Biomater. Sci., 2021, 9, 10-22.(ESI高被引论文)

(6) T. Chang, C. Liu, K. Lu, Y. Wu, M. Xu,Q. Yu*, Z. Shen*, T. Jiang*, Y. Zhang*, Biomaterials based cardiac patches for the treatment of myocardial infarction,J. Mater. Sci. Technol., 2021, 94, 77-89.

(7) Y. Qu, K. Lu, Y. Zheng, C. Huang, G. Wang*, Y. Zhang*,Q. Yu*, Photothermal scaffolds/surfaces for regulation of cell behaviors,Bioactive Mater., 2022, 8, 449-477.

(8) 于谦*,陈红,具有杀菌-释菌功能转换的智能抗菌表面,高分子学报, 2020, 51, 319-325.(封面论文)

(9) Y. Qu, Y. Zhang,Q. Yu*, H. Chen, Surface-Mediated Intracellular Delivery by Physical Membrane Disruption,ACS Appl. Mater. Interfaces, 2020, 12, 31054-31078.

(10) T. Wei, Q. Yu*, H. Chen, Responsive and Synergistic Antibacterial Coatings: Fighting against Bacteria in a Smart and Effective Way,Adv. Healthcare Mater., 2019, 8, 1801381.(ESI热点论文、ESI高被引论文、封面论文)

(11) J. Wu, Y. Qu, Q. Yu*, H. Chen, Gold Nanoparticle Layer: A Versatile Nanostructured Platform For Biomedical Applications,Mater. Chem. Front., 2018, 2, 2175-2190.

(12) T. Wei, Z. Tang, Q. Yu*, H. Chen, Smart Antibacterial Surfaces with Switchable Bacteria-Killing and Bacteria-Releasing Capabilities,ACS Appl. Mater. Interfaces, 2017, 9, 37511-37523.(ESI热点论文)

(13) W. Zhan, T. Wei, Q. Yu*, H. Chen, Fabrication of Supramolecular Bioactive Surfaces via β-Cyclodextrin-Based Host–Guest Interactions,ACS Appl. Mater. Interfaces, 2018, 10, 36585-36601.

(14) Q. Yu*, L. K. Ista, R. Gu, S. Zauscher, G. P. Lopez*, Nanopatterned Polymer Brushes: Conformation, Fabrication And Applications,Nanoscale, 2016, 8, 680-700.

(15) Q. Yu, Z. Wu, H. Chen, Dual-Function Antibacterial Surfaces For Biomedical Applications,Acta Biomater., 2015, 16, 1-13.(ESI高被引论文)

研究论文

(1) H. Zhang, Y. Zou, K. Lu, Y. Wu, Y. Lin, J. Cheng, C. Liu, H. Chen,Y. Zhang*,Q. Yu*,A nanoplatform with oxygen self-supplying and heat-sensitizing capabilities enhances the efficacy of photodynamic therapy in eradicating multidrug-resistant biofilms,J. Mater. Sci. Technol., 2024, 169, 209-219.

(2) K. Lu, Y. Lin, H. Zhang, J. Cheng, Y. Qu, Y. Wu, Y. Zhang, Y. Zou, Y. Zhang*,Q. Yu*, H. Chen*, Enhanced intracellular delivery and cell harvest using a candle soot-based photothermal platform with dual-stimulus responsiveness,ACS Appl. Mater. Interfaces, 2023, 15, 40153-40162.

(3) Y. Lin, K. Lu, H. Zhang, Y. Zou, H. Chen, Y. Zhang*,Q. Yu*, Multifunctional coatings based on candle soot with photothermal bactericidal property and desired biofunctionality,J. Colloid Interface Sci., 2023, 649, 986-995.

(4) Y. Lin, H. Zhang, Y. Zou, K. Lu, L. Li, Y. Wu, J. Cheng, Y. Zhang*, H. Chen,Q. Yu*, Superhydrophobic photothermal coatings based on candle soot for prevention of biofilm formation,J. Mater. Sci. Technol., 2023, 132, 18-26.(ESI高被引论文)

(5) C. Liu, Y. Wu, H. Yang, K. Lu, H. Zhang, Y. Wang, J. Wang, L. Ruan, Z. Shen*, Q. Yu*,Y. Zhang*, An injectable alginate/fibrin hydrogel encapsulated with cardiomyocytes and VEGF for myocardial infarction treatment,J. Mater. Sci. Technol., 2023, 143, 198-206.

(6) Y. Wang, J. Wang, C. Liu, J. Li, K. Lu,Q. Yu*, Y. Zhang*, Z. Shen*, Injectable decellularized extracellular matrix hydrogel loaded with exosomes encapsulating curcumin for prevention of cardiac fibrosis after myocardial infarction,J. Mater. Sci. Technol., 2023, 167, 50-58.

(7) Y. Wu, D. Jia, K. Lu, H. Zhang, C. Liu, Y. Lin, J. Cheng, Y. Zou, H. Xu, H. Chen, Y. Zhang*,Q. Yu*, Bacterial cellulose-based dressings with photothermal bactericidal activity and pro-angiogenic ability for infected wound healing,J. Mater. Sci. Technol., 2023, 160, 76-85.

(8) K. Wu, Y. Wang, H. Yang, Y. Chen, K. Lu, Y. Wu, C. Liu, H. Zhang, H. Meng,Q. Yu*, Y. Zhang*, Z. Shen*, Injectable Decellularized Extracellular Matrix Hydrogel Containing Stromal Cell-Derived Factor 1 Promotes Transplanted Cardiomyocyte Engraftment and Functional Regeneration after Myocardial Infarction,ACS Appl. Mater. Interfaces, 2023, 15, 2578-2589.

(9) J. Yuan, H. Yang, C. Liu, L. Shao, H. Zhang, K. Lu, J. Wang, Y. Wang,Q. Yu*, Y. Zhang*, Y. Yu*, Z. Shen*, Microneedle Patch Loaded with Exosomes Containing MicroRNA-29b Prevents Cardiac Fibrosis after Myocardial Infarction,Adv. Healthcare Mater., 2023, 12, 2202959.(封底论文)

(10) Y. Zou, C. Liu, H. Zhang, Y. Wu, Y. Lin, J. Cheng, K. Lu, L. Li, Y. Zhang*, H. Chen,Q. Yu*, Three lines of defense: A multifunctional coating with anti-adhesion, bacteria-killing and anti-quorum sensing properties for preventing biofilm formation of Pseudomonas aeruginosa,Acta Biomater., 2022, 151, 254-263.

(11) Y. Qu, X. Zhu, R. Kong, K. Lu, T. Fan,Q. Yu*, G. Wang*, Dual-functional antibacterial hybrid film with antifouling and NIR-activated bactericidal properties,Composites, Part B, 2022, 244, 110143.

(12) T. Chang, C. Liu, H. Yang, K. Lu, Y. Han, Y. Zheng, H. Huang, Y. Wu, Y. Song,Q. Yu*, Z. Shen*, T. Jiang*, Y. Zhang*, Fibrin-based cardiac patch containing neuregulin-1 for heart repair after myocardial infarction,Colloids Surf., B, 2022, 220, 112936.

(13) K. Lu, Y. Qu, Y. Lin, L. Li, Y. Wu, Y. Zou, T. Chang, Y. Zhang*,Q. Yu*, H. Chen*, A Photothermal Nanoplatform with Sugar-Triggered Cleaning Ability for High-Efficiency Intracellular Delivery,ACS Appl. Mater. Interfaces, 2022, 14, 2618-2628.

(14) L. Li, G. Li, Y. Wu, Y. Lin, Y. Qu, Y. Wu, K. Lu, Y. Zou, H. Chen,Q. Yu*, Y. Zhang*, Dual-functional bacterial cellulose modified with phase-transitioned proteins and gold nanorods combining antifouling and photothermal bactericidal properties,J. Mater. Sci. Technol., 2022, 110, 14-23.

(15) Y. Zou, K. Lu, Y. Lin, Y. Wu, Y. Wang, L. Li, C. Huang, Y. Zhang*, J. L. Brash, H. Chen,Q. Yu*, Dual-Functional Surfaces Based on an Antifouling Polymer and a Natural Antibiofilm Molecule: Prevention of Biofilm Formation without Using Biocides,ACS Appl. Mater. Interfaces, 2021, 13, 45191-45200.

(16) Y. Wu, T. Chang, W. Chen, X. Wang, J. Li, Y. Chen, Y. Yu, Z. Shen*,Q. Yu*, Y. Zhang*, Release of VEGF and BMP9 from injectable alginate based composite hydrogel for treatment of myocardial infarction,Bioact. Mater., 2021, 6, 520-528.

(17) Y. Qu, Y. Zheng, L. Yu, Y. Zhou, Y. Wang, Y. Zhang,Q. Yu*, H. Chen*, A Universal Platform for High‐Efficiency “Engineering” Living Cells: Integration of Cell Capture, Intracellular Delivery of Biomolecules, and Cell Harvesting Functions,Adv. Funct. Mater., 2020, 30, 1906362.

(18) Y. Wang, T. Wei, Y. Qu, Y. Zhou, Y. Zheng, C. Huang, Y. Zhang,Q. Yu*, H. Chen, Smart, Photothermally Activated, Antibacterial Surfaces with Thermally Triggered Bacteria-Releasing Properties,ACS Appl. Mater. Interfaces, 2020, 12, 21283-21291.

(19) Y. Zheng, Y. Wu, Y. Zhou, J. Wu, X. Wang, Y. Qu, Y. Wang, Y. Zhang*,Q. Yu*, Photothermally Activated Electrospun Nanofiber Mats for High-Efficiency Surface-Mediated Gene Transfection,ACS Appl. Mater. Interfaces, 2020, 12, 7905-7914.

(20) Y. Zhou, Y. Zheng, T. Wei, Y. Qu, Y. Wang, W. Zhan, Y. Zhang, G. Pan, D. Li*,Q. Yu*, H. Chen, Multistimulus Responsive Biointerfaces with Switchable Bioadhesion and Surface Functions,ACS Appl. Mater. Interfaces, 2020, 12, 5447-5455.

(21) J. Wu, Y. Zheng, S. Jiang, Y. Qu, T. Wei, W. Zhan, L. Wang,Q. Yu*, H. Chen*, Two-in-One Platform for High-Efficiency Intracellular Delivery and Cell Harvest: When a Photothermal Agent Meets a Thermoresponsive Polymer,ACS Appl. Mater. Interfaces, 2019, 11, 12357-12366.

(22) W. Zhan, Y. Qu, T. Wei, C. Hu, Y. Pan,Q. Yu*, H. Chen*, Sweet Switch: Sugar-Responsive Bioactive Surfaces Based on Dynamic Covalent Bonding,ACS Appl. Mater. Interfaces, 2018, 10, 10647-10655.

(23) T. Wei, W. Zhan,Q. Yu*, H. Chen*, Smart Biointerface with Photoswitched Functions between Bactericidal Activity and Bacteria-Releasing Ability,ACS Appl. Mater. Interfaces, 2017, 9, 25767-25774.

(24) J. Wu, H. Xue, Z. Lyu, Z. Li, Y. Qu, Y. Xu, L. Wang*,Q. Yu*, H. Chen, Intracellular Delivery Platform for “Recalcitrant” Cells: When Polymeric Carrier Marries Photoporation,ACS Appl. Mater. Interfaces, 2017, 9, 21593-21598.

(25) W. Zhan, T. Wei, L. Cao, C. Hu, Y. Qu,Q. Yu*, H. Chen*, Supramolecular Platform with Switchable Multivalent Affinity: Photo-Reversible Capture and Release of Bacteria,ACS Appl. Mater. Interfaces, 2017, 9, 3505-3513.

(26) L. Cao, Y. Qu, C. Hu, T. Wei, W. Zhan,Q. Yu*, H. Chen*, A Universal and Versatile Approach for Surface Bio-Functionalization: Layer-by-Layer Assembly Meets Host-Guest Chemistry,Adv. Mater. Interfaces, 2016, 3, 1600600.

(27) H. Du, C. Li, Y. Luan, Q. Liu, W. Yang,Q. Yu*, D. Li*, J. L. Brash, H. Chen, An Antithrombotic Hydrogel with Thrombin-Responsive Fibrinolytic Activity: Breaking Down the Clot as It Forms,Mater. Horiz., 2016, 3, 556-562.(封面论文)

(28) Z. Lyu, F. Zhou, Q. Liu, H. Xue,Q. Yu*, H. Chen*, A Universal Platform For Macromolecular Delivery into Cells Using Gold Nanoparticle Layers via the Photoporation Effect,Adv. Funct. Mater., 2016, 26, 5787-5795.(封面论文)

(29) T. Wei,Q. Yu*, W. Zhan, H. Chen*, A Smart Antibacterial Surface for the On-Demand Killing and Releasing of Bacteria,Adv. Healthcare Mater., 2016, 5, 449-456.(封面论文)

(30) T. Wei, W. Zhan, L. Cao, C. Hu, Y. Qu,Q. Yu*, H. Chen*, Multifunctional and Regenerable Antibacterial Surfaces Fabricated Using a Universal Strategy,ACS Appl. Mater. Interfaces, 2016, 8, 30048-30057.

(31) W. Zhan, X. Shi,Q. Yu*, Z. Lyu, L. Cao, H. Du, Q. Liu, X. Wang, G. Chen, D. Li, J. L. Brash, H. Chen*, Bioinspired Blood Compatible Surface Having Combined Fibrinolytic and Vascular Endothelium-Like Properties via a Sequential Coimmobilization Strategy,Adv. Funct. Mater., 2015, 25, 5206-5213.